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. 1987 Apr;68(1):78–85.

Antibodies to tubulin in patients with parasitic infections.

M K Howard 1, K Gull 1, M A Miles 1
PMCID: PMC1542701  PMID: 3115642

Abstract

Sera from a total of 268 patients with protozoan, helminth, bacterial (leprosy and tuberculosis) infections or appropriate controls, were assayed for anti-tubulin antibodies in an indirect enzyme-linked immunosorbent assay (ELISA), using purified tubulin as antigen. Levels of serum anti-tubulin antibody were significantly elevated in 67% of patients with visceral leishmaniasis, in 60% of patients with cutaneous leishmaniasis, in 89% of patients with onchocerciasis, in 100% of patients with schistosomiasis, and in 94% of patients with leprosy. Little or no increase in anti-tubulin antibody levels was seen in sera from patients with malaria (Plasmodium vivax) or tuberculosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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