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. 1987 Jun;68(3):712–718.

Origin of human mast cells studied by dual immunofluorescence.

E F Rimmer 1, M A Horton 1
PMCID: PMC1542749  PMID: 3308221

Abstract

Previous reports have suggested that mast cells derive either directly from basophils or mononuclear phagocytes, or from a common myeloid precursor. We have used monoclonal antibodies to investigate expression by normal human tissue mast cells of antigens characteristic of other haemopoietic lineages. We find that mast cells express panhaemopoietic markers, but not antigens typical of either myeloid or lymphoid cells. We propose, therefore, that mast cells form a distinct lineage, only distantly-related to other haemopoietic cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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