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. 1975 Mar;50(3):187–190. doi: 10.1136/adc.50.3.187

Calcium balance in children treated with diphosphonates.

W S Uttley, N R Belton, J Syme, H Sheppard
PMCID: PMC1544507  PMID: 167664

Abstract

Serial mineral balances have been obtained in 3 children undergoing therapy with EHDP (ethane-1-hydroxy-1, 1-diphosphonate) for diseases involving ectopic calcification. Although clinical outcome was not uniformly satisfactory, all cases showed an overall reduction in calcium balance. This was due to increased faecal excretion of calcium and was most marked after a long duration of therapy. Although these results conflict with reported experience in adults, they are in agreement with published observations of the effects of EHDP on calcium absorption in experimental animals.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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