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. 1975 Jun;50(6):467–471. doi: 10.1136/adc.50.6.467

Plasma gastrin in congenital hypertrophic pyloric stenosis

A hypothesis disproved?

I M Rogers, I K Drainer, M R Moore, K D Buchanan
PMCID: PMC1544539  PMID: 238476

Abstract

Fasting plasma gastrin levels were measured in babies with pyloric stenosis and in normal babies of similar age. There was no difference in gastrin levels either before or after operation between the babies with pyloric stenosis and normal babies. Similarly, neither the fasting blood glucose nor the fasting gastric pH of the babies with pyloric stenosis differed significantly from the values obtained in normal babies.

Our findings do not support the hypothesis that gastrin in the fasting baby has an aetiological role in the development of hypertrophic pyloric stenosis of infancy. An alternative hypothesis is suggested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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