Abstract
Using a modification of the forced oscillation technique we have measured respiratory resistance before and after nebulised salbutamol therapy in 32 wheezing children aged 7 months to 3 years 7 monts. 12 of the children were also studied in a total body plethysmograph. No child under 18 months of aged showed a greater than 5% fall in resistance or any fall in thoracic gas volume. In contrast, 18 of 20 children over 20 months of age showed a fall in resistance greater than 20%.
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Selected References
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- Cogswell J. J. Forced oscillation technique for determination of resistance to breathing in children. Arch Dis Child. 1973 Apr;48(4):259–266. doi: 10.1136/adc.48.4.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DUBOIS A. B., BOTELHO S. Y., BEDELL G. N., MARSHALL R., COMROE J. H., Jr A rapid plethysmographic method for measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects. J Clin Invest. 1956 Mar;35(3):322–326. doi: 10.1172/JCI103281. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DUBOIS A. B., BOTELHO S. Y., COMROE J. H., Jr A new method for measuring airway resistance in man using a body plethysmograph: values in normal subjects and in patients with respiratory disease. J Clin Invest. 1956 Mar;35(3):327–335. doi: 10.1172/JCI103282. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DUBOIS A. B., BRODY A. W., LEWIS D. H., BURGESS B. F., Jr Oscillation mechanics of lungs and chest in man. J Appl Physiol. 1956 May;8(6):587–594. doi: 10.1152/jappl.1956.8.6.587. [DOI] [PubMed] [Google Scholar]
- Doershuk C. F., Downs T. D., Matthews L. W., Lough M. D. A method for ventilatory measurements in subjects 1 month--5 years of age: Normal results and observations in disease. Pediatr Res. 1970 Mar;4(2):165–174. doi: 10.1203/00006450-197003000-00007. [DOI] [PubMed] [Google Scholar]
- Lenney W., Milner A. D. Recurrent wheezing in the preschool child. Arch Dis Child. 1978 Jun;53(6):468–473. doi: 10.1136/adc.53.6.468. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Radford M. Effect of salbutamol in infants with wheezy bronchitis. Arch Dis Child. 1975 Jul;50(7):535–538. doi: 10.1136/adc.50.7.535. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Radford M. Measurement of airway resistance and thoracic gas volume in infancy. Arch Dis Child. 1974 Aug;49(8):611–615. doi: 10.1136/adc.49.8.611. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rutter N., Milner A. D., Hiller E. J. Effect of bronchodilators on respiratory resistance in infants and young children with bronchiolitis and wheezy bronchitis. Arch Dis Child. 1975 Sep;50(9):719–722. doi: 10.1136/adc.50.9.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stocks J., Levy N. M., Godfrey S. A new apparatus for the accurate measurement of airway resistance in infancy. J Appl Physiol Respir Environ Exerc Physiol. 1977 Jul;43(1):155–159. doi: 10.1152/jappl.1977.43.1.155. [DOI] [PubMed] [Google Scholar]
- Williams H., McNicol K. N. Prevalence, natural history, and relationship of wheezy bronchitis and asthma in children. An epidemiological study. Br Med J. 1969 Nov 8;4(5679):321–325. doi: 10.1136/bmj.4.5679.321. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Woolcock A. J., Read J. Lung volumes in exacerbations of asthma. Am J Med. 1966 Aug;41(2):259–273. doi: 10.1016/0002-9343(66)90021-0. [DOI] [PubMed] [Google Scholar]
