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. 1978 Jul;53(7):540–544. doi: 10.1136/adc.53.7.540

Group B streptococci in pharyngeal aspirates at birth and the early detection of neonatal sepsis.

M P Slack, R T Mayon-White
PMCID: PMC1544991  PMID: 356751

Abstract

The pharyngeal aspirates collected from 400 babies at the time of delivery were examined for the presence of bacteria, especially group B streptococci. Aspirates from 79 babies were found to contain viable bacteria, including 4 with group B streptococci; one of these 4 babies developed streptococcal meningitis within 24 hours. The group B streptococci were seen on a Gram-stained film of the aspirate, and were detectable by coagglutination and countercurrent immunoelectrophoresis within 4 hours and by culture after 24 hours. Examination of pharyngeal aspirates may be of value as a screening test for neonatal sepsis.

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Selected References

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  1. Ablow R. C., Driscoll S. G., Effmann E. L., Gross I., Jolles C. J., Uauy R., Warshaw J. B. A comparison of early-onset group B steptococcal neonatal infection and the respiratory-distress syndrome of the newborn. N Engl J Med. 1976 Jan 8;294(2):65–70. doi: 10.1056/NEJM197601082940201. [DOI] [PubMed] [Google Scholar]
  2. BENIRSCHKE K., CLIFFORD S. H. Intrauterine bacterial infection of the newborn infant: frozen sections of the cord as an aid to early detection. J Pediatr. 1959 Jan;54(1):11–18. doi: 10.1016/s0022-3476(59)80031-7. [DOI] [PubMed] [Google Scholar]
  3. BLANC W. A. Pathways of fetal and early neonatal infection. Viral placentitis, bacterial and fungal chorioamnionitis. J Pediatr. 1961 Oct;59:473–496. doi: 10.1016/s0022-3476(61)80232-1. [DOI] [PubMed] [Google Scholar]
  4. Baker C. J., Barrett F. F., Gordon R. C., Yow M. D. Suppurative meningitis due to streptococci of Lancefield group B: a study of 33 infants. J Pediatr. 1973 Apr;82(4):724–729. doi: 10.1016/s0022-3476(73)80606-7. [DOI] [PubMed] [Google Scholar]
  5. Baker C. J., Barrett F. F. Transmission of group B streptococci among parturient women and their neonates. J Pediatr. 1973 Dec;83(6):919–925. doi: 10.1016/s0022-3476(73)80524-4. [DOI] [PubMed] [Google Scholar]
  6. Baker C. J., Kasper D. L. Correlation of maternal antibody deficiency with susceptibility to neonatal group B streptococcal infection. N Engl J Med. 1976 Apr 1;294(14):753–756. doi: 10.1056/NEJM197604012941404. [DOI] [PubMed] [Google Scholar]
  7. Bergqvist G., Hurvell B., Malmborg A. S., Rylander M., Tunell R. Neonatal infections caused by group B streptococci. Scand J Infect Dis. 1971;3(2):157–162. doi: 10.3109/inf.1971.3.issue-2.10. [DOI] [PubMed] [Google Scholar]
  8. Dajani A. S. Rapid identification of beta hemolytic streptococci by counterimmunoelectrophoresis. J Immunol. 1973 Jun;110(6):1702–1705. [PubMed] [Google Scholar]
  9. EICKHOFF T. C., KLEIN J. O., DALY A. K., INGALL D., FINLAND M. NEONATAL SEPSIS AND OTHER INFECTIONS DUE TO GROUP B BETA-HEMOLYTIC STREPTOCOCCI. N Engl J Med. 1964 Dec 10;271:1221–1228. doi: 10.1056/NEJM196412102712401. [DOI] [PubMed] [Google Scholar]
  10. Echeverria P. Observations concerning infections with beta hemolytic streptococci, not group A or D, in neonates. J Pediatr. 1973 Sep;83(3):499–500. doi: 10.1016/s0022-3476(73)80285-9. [DOI] [PubMed] [Google Scholar]
  11. El-Refaie M., Dulake C. Counter-current immunoelectrophoresis for the diagnosis of pneumococcal chest infection. J Clin Pathol. 1975 Oct;28(10):801–806. doi: 10.1136/jcp.28.10.801. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Ferrieri P., Cleary P. P., Seeds A. E. Epidemiology of group-B streptococcal carriage in pregnant women and newborn infants. J Med Microbiol. 1977 Feb;10(1):103–114. doi: 10.1099/00222615-10-1-103. [DOI] [PubMed] [Google Scholar]
  13. Franciosi R. A., Knostman J. D., Zimmerman R. A. Group B streptococcal neonatal and infant infections. J Pediatr. 1973 Apr;82(4):707–718. doi: 10.1016/s0022-3476(73)80604-3. [DOI] [PubMed] [Google Scholar]
  14. Galask R. P., Snyder I. S. Bacterial inhibition by amniotic fluid. Am J Obstet Gynecol. 1968 Dec 1;102(7):949–955. doi: 10.1016/0002-9378(68)90453-5. [DOI] [PubMed] [Google Scholar]
  15. HOOD M., JANNEY A., DAMERON G. Beta hemolytic streptococcus group B associated with problems of the perinatal period. Am J Obstet Gynecol. 1961 Oct;82:809–818. doi: 10.1016/s0002-9378(16)36146-4. [DOI] [PubMed] [Google Scholar]
  16. Hill H. R., Riter M. E., Menge S. K., Johnson D. R., Matsen J. M. Rapid identification of group B streptococci by counterimmunoelectrophoresis. J Clin Microbiol. 1975 Feb;1(2):188–191. doi: 10.1128/jcm.1.2.188-191.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Howard J. B., McCracken G. H., Jr The spectrum of group B streptococcal infections in infancy. Am J Dis Child. 1974 Dec;128(6):815–818. doi: 10.1001/archpedi.1974.02110310063011. [DOI] [PubMed] [Google Scholar]
  18. Mims L. C., Medawar M. S., Perkins J. R., Grubb W. R. Predicting neonatal infections by evaluation of the gastric aspirate: a study in two hundred and seven patients. Am J Obstet Gynecol. 1972 Sep 15;114(2):232–238. doi: 10.1016/0002-9378(72)90064-6. [DOI] [PubMed] [Google Scholar]
  19. Overbach A. M., Daniel S. J., Cassady G. The value of umbilical cord histology in the management of potential perinatal infection. J Pediatr. 1970 Jan;76(1):22–31. doi: 10.1016/s0022-3476(70)80125-1. [DOI] [PubMed] [Google Scholar]
  20. Ramos A., Stern L. Relationship of premature rupture of the membranes to gastric fluid aspirate in the newborn. Am J Obstet Gynecol. 1969 Dec 15;105(8):1247–1251. doi: 10.1016/0002-9378(69)90298-1. [DOI] [PubMed] [Google Scholar]
  21. SMITH J. W., BLOOMFIELD A. L. The development of the aerobic bacterial flora of the throat in newborn babies. J Pediatr. 1950 Jan;36(1):51–60. doi: 10.1016/s0022-3476(50)80179-8. [DOI] [PubMed] [Google Scholar]
  22. Scanlon J. The early detection of neonatal sepsis by examination of liquid obtained from the external ear canal. J Pediatr. 1971 Aug;79(2):247–249. doi: 10.1016/s0022-3476(71)80108-7. [DOI] [PubMed] [Google Scholar]
  23. Yeung C. Y., Tam A. S. Gastric aspirate findings in neonatal pneumonia. Arch Dis Child. 1972 Oct;47(255):735–740. doi: 10.1136/adc.47.255.735. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Yow M. Editorial: Group B streptococci: a serious threat to the neonate. JAMA. 1974 Nov 25;230(8):1177–1178. [PubMed] [Google Scholar]

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