Abstract
Neurological complications in beta-thalassaemia major are uncommon, with cerebral ischaemic episodes related to severe anaemia or convulsions as the most usual manifestations. Two such cases of children of 6 and 8 years are reported. Cerebral venous infarction is advanced as the probable cause of the symptoms. Caution should be exercised in giving rapid, large blood transfusions to thalassaemic patients adapted to long-standing severe anaemia.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Logothetis J., Constantoulakis M., Economidou J., Stefanis C., Hakas P., Augoustaki O., Sofroniadou K., Loewenson R., Bilek M. Thalassemia major (homozygous beta-thalassemia). A survey of 138 cases with emphasis on neurologic and muscular aspects. Neurology. 1972 Mar;22(3):294–304. doi: 10.1212/wnl.22.3.294. [DOI] [PubMed] [Google Scholar]
- Orsini A., Soulayrol R., Tramini F., Tasso-Perrimond A. M. Les manifestations nerveuses au cours de la thalassémie (etude critique du concept de syndrome neuro-hémolytique thalassémique) Pediatrie. 1967 Oct-Nov;22(7):771–784. [PubMed] [Google Scholar]
- WITZLEBEN C. L., WYATT J. P. The effect of long survival on the pathology of thalassaemia major. J Pathol Bacteriol. 1961 Jul;82:1–12. [PubMed] [Google Scholar]