Skip to main content
NCBI home page
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1978 Sep;53(9):710–713. doi: 10.1136/adc.53.9.710

House dust mite sensitivity in childhood asthma.

J O Warner, J F Price
PMCID: PMC1545128  PMID: 718239

Abstract

The clinical features of perennial asthmatic children with a skin or bronchial reaction to the house dust mite (Dermatophagoides pteronyssinus) were compared with those of asthmatic children without mite sensitivity. Mite sensitive asthma was characterised by an early age of onset of symptoms, these being predominantly nocturnal. A history of wheezing precipitated by dust exposure, during vacuuming, bedmaking, or dusting was present in 52% of cases. Asthmatic children with mite sensitivity were more likely to have been born at the time of the year when mite counts were highest. This was consistent with the idea that allergy may be associated with a period of susceptibility to sensitisation in early infancy.

Full text

PDF
710

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aas K. Bronchial provocation tests in asthma. Arch Dis Child. 1970 Apr;45(240):221–228. doi: 10.1136/adc.45.240.221. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Björkstén F., Suoniemi I. Dependence of immediate hypersensitivity on the month of birth. Clin Allergy. 1976 Mar;6(2):165–171. doi: 10.1111/j.1365-2222.1976.tb01894.x. [DOI] [PubMed] [Google Scholar]
  3. Blythe M. E. Some aspects of the ecological study of the house dust mites. Br J Dis Chest. 1976 Jan;70(1):3–31. doi: 10.1016/0007-0971(76)90003-6. [DOI] [PubMed] [Google Scholar]
  4. Brown H. M., Filer J. L. Role of mites in allergy to house dust. Br Med J. 1968 Sep 14;3(5619):646–647. doi: 10.1136/bmj.3.5619.646. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bryant D. H., Burns M. W., Lazarus L. The correlation between skin tests, bronchial provocation tests and the serum level of IgE specific for common allergens in patients with asthma. Clin Allergy. 1975 Jun;5(2):145–157. doi: 10.1111/j.1365-2222.1975.tb01847.x. [DOI] [PubMed] [Google Scholar]
  6. Cochrane G. M., Clark J. H. A survey of asthma mortality in patients between ages 35 and 64 in the Greater London hospitals in 1971. Thorax. 1975 Jun;30(3):300–305. doi: 10.1136/thx.30.3.300. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gervais P., Reinberg A., Gervais C., Smolensky M., DeFrance O. Twenty-four-hour rhythm in the bronchial hyperreactivity to house dust in asthmatics. J Allergy Clin Immunol. 1977 Mar;59(3):207–213. doi: 10.1016/0091-6749(77)90151-8. [DOI] [PubMed] [Google Scholar]
  8. Hetzel M. R., Clark T. J., Houston K. Physiological patterns in early morning asthma. Thorax. 1977 Aug;32(4):418–423. doi: 10.1136/thx.32.4.418. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. McAllen M. K., Assem E. S., Maunsell K. House-dust mite asthma. Results of challenge tests on five criteria with Dermatophagoides pteronyssinus. Br Med J. 1970 May 30;2(5708):501–504. doi: 10.1136/bmj.2.5708.501. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Mcnicol K. N., Macnicol K. N., Williams H. B. Spectrum of asthma in children. I. Clinical and physiological components. Br Med J. 1973 Oct 6;4(5883):7–11. doi: 10.1136/bmj.4.5883.7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Pearson D. J., Freed D. L., Taylor G. Respiratory allergy and month of birth. Clin Allergy. 1977 Jan;7(1):29–33. doi: 10.1111/j.1365-2222.1977.tb01421.x. [DOI] [PubMed] [Google Scholar]
  12. Sarsfield J. K. Role of house-dust mites in childhood asthma. Arch Dis Child. 1974 Sep;49(9):711–715. doi: 10.1136/adc.49.9.711. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Smith J. M. Incidence of atopic disease. Med Clin North Am. 1974 Jan;58(1):3–24. doi: 10.1016/s0025-7125(16)32173-3. [DOI] [PubMed] [Google Scholar]
  14. Soothill J. F., Stokes C. R., Turner M. W., Norman A. P., Taylor B. Predisposing factors and the development of reaginic allergy in infancy. Clin Allergy. 1976 Jul;6(4):305–319. doi: 10.1111/j.1365-2222.1976.tb01911.x. [DOI] [PubMed] [Google Scholar]
  15. Spector S. L., Farr R. S. Bronchial inhalation procedures in asthmatics. Med Clin North Am. 1974 Jan;58(1):71–84. doi: 10.1016/s0025-7125(16)32178-2. [DOI] [PubMed] [Google Scholar]
  16. Stenius B., Wide L. Reaginic antibody (IgE), skin, and provocation tests to Dermatophagoides culinae and house dust in respiratory allergy. Lancet. 1969 Aug 30;2(7618):455–458. doi: 10.1016/s0140-6736(69)90165-2. [DOI] [PubMed] [Google Scholar]
  17. Taylor B., Norman A. P., Orgel H. A., Stokes C. R., Turner M. W., Soothill J. F. Transient IgA deficiency and pathogenesis of infantile atopy. Lancet. 1973 Jul 21;2(7821):111–113. doi: 10.1016/s0140-6736(73)93060-2. [DOI] [PubMed] [Google Scholar]
  18. VOORHORST R., SPIEKSMA-BOEZEMAN M. I., SPIEKSMA F. T. IS A MITE (DERMATOPHAGOIDES SP.) THE PRODUCER OF THE HOUSE-DUST ALLERGEN? Allerg Asthma (Leipz) 1964;10:329–334. [PubMed] [Google Scholar]
  19. Viner A. S., Jackman N. Retrospective survey of 1271 patients diagnosed as perennial rhinitis. Clin Allergy. 1976 May;6(3):251–259. doi: 10.1111/j.1365-2222.1976.tb01904.x. [DOI] [PubMed] [Google Scholar]
  20. Warner J. O. Significance of late reactions after bronchial challenge with house dust mite. Arch Dis Child. 1976 Dec;51(12):905–911. doi: 10.1136/adc.51.12.905. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES