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. 1979 Jan;54(1):74–76. doi: 10.1136/adc.54.1.74

Reye's syndrome associated with respiratory syncytial virus infection.

N Griffin, J W Keeling, A H Tomlinson
PMCID: PMC1545194  PMID: 420528

Abstract

An upper respiratory tract infection in a 22-month-old boy was followed by rapid loss of consciousness, hypoglycaemia, uraemia, and death. Necropsy examination showed fatty change of liver and kidneys, severe cerebral oedema, bronchiolitis, and endocardial fibroelastosis affecting the left ventricle. Immunofluorescence staining showed infection with respiratory syncytial virus (RSV). The clinical and pathological findings were those of Reye's syndrome, not previously reported accompanying RSV infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gardner P. S., McQuillin J., Court S. D. Speculation on pathogenesis in death from respiratory syncytial virus infection. Br Med J. 1970 Feb 7;1(5692):327–330. doi: 10.1136/bmj.1.5692.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Glasgow J. F., Ferris J. A. Encephalopathy and visceral fatty infiltration of probable toxic aetiology. Lancet. 1968 Mar 2;1(7540):451–453. doi: 10.1016/s0140-6736(68)92781-5. [DOI] [PubMed] [Google Scholar]
  3. Hogan G. R., Ryan N. J., Hayes A. W. Aflatoxin B1 and Reye's syndrome. Lancet. 1978 Mar 11;1(8063):561–561. doi: 10.1016/s0140-6736(78)90592-5. [DOI] [PubMed] [Google Scholar]
  4. Linnemann C. C., Jr, Shea L., Partin J. C., Schubert W. K., Schiff G. M. Reye's syndrome: epidemiologic and viral studies, 1963-1974. Am J Epidemiol. 1975 Jun;101(6):517–526. doi: 10.1093/oxfordjournals.aje.a112123. [DOI] [PubMed] [Google Scholar]
  5. McQuillin J., Gardner P. S. Rapid diagnosis of respiratory syncytial virus infection by immunofluorescent antibody techniques. Br Med J. 1968 Mar 9;1(5592):602–605. doi: 10.1136/bmj.1.5592.602. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. REYE R. D., MORGAN G., BARAL J. ENCEPHALOPATHY AND FATTY DEGENERATION OF THE VISCERA. A DISEASE ENTITY IN CHILDHOOD. Lancet. 1963 Oct 12;2(7311):749–752. doi: 10.1016/s0140-6736(63)90554-3. [DOI] [PubMed] [Google Scholar]
  7. Shield L. K., Coleman T. L., Markesbery W. R. Methyl bromide intoxication: neurologic features, including simulation of Reye syndrome. Neurology. 1977 Oct;27(10):959–962. doi: 10.1212/wnl.27.10.959. [DOI] [PubMed] [Google Scholar]

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