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. 1976 May;51(5):344–348. doi: 10.1136/adc.51.5.344

Congenital nephrotic syndrome of Finnish type. Study of 75 patients.

N P Huttunen
PMCID: PMC1545982  PMID: 938078

Abstract

Seventy-five patients with congenital nephrotic syndrome of Finnish type were identified in Finland in the period 1965-1973, giving an incidence of 12-2/10(5). A large placenta and proteinuria from birth are the hallmarks of the disease. About one-quarter of the patients had oedema and/or abdominal distension at birth and in all cases the full nephrotic syndrome was documented before 2 months. More than half of the patients died before 6 months and none lived longer than 2 years 3 months. A slight rise in blood urea nitrogen or serum creatinine levels occurred in 14 cases, but in none of these did a frank uraemia develop before death. Infection appeared to be the immediate cause of death in 31% of the cases; in 43% no cause of death other than congenital nephrotic syndrome could be shown. Thrombi in large vessels were found in 11 out of 58 necropsies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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