Abstract
The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour creatinine clearance. It was found to be superior to the creatinine clearance overall, and was as good, even if all results involving suspect 24-hour-urine collections were eliminated from analysis. The formula in SI usage is: GFR/SA (ml/min per 1-73 m2SA) = 38 Ht (cm)1Pc (mumol/l).
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Selected References
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- Chantler C., Barratt T. M. Estimation of glomerular filtration rate from plasma clearance of 51-chromium edetic acid. Arch Dis Child. 1972 Aug;47(254):613–617. doi: 10.1136/adc.47.254.613. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cockcroft D. W., Gault M. H. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31–41. doi: 10.1159/000180580. [DOI] [PubMed] [Google Scholar]
- DOOLAN P. D., ALPEN E. L., THEIL G. B. A clinical appraisal of the plasma concentration and endogenous clearance of creatinine. Am J Med. 1962 Jan;32:65–79. doi: 10.1016/0002-9343(62)90183-3. [DOI] [PubMed] [Google Scholar]
- Donckerwolcke R. A., Sander P. C., van Stekelenburg G. J., Stoop J. W., Tiddens H. A. Serum creatinine values in healthy children. Acta Paediatr Scand. 1970 Jul;59(4):399–402. doi: 10.1111/j.1651-2227.1970.tb15534.x. [DOI] [PubMed] [Google Scholar]
- Ghazali S., Barratt T. M. Urinary excretion of calcium and magnesium in children. Arch Dis Child. 1974 Feb;49(2):97–101. doi: 10.1136/adc.49.2.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jelliffe R. W. Estimation of creatinine clearance when urine cannot be collected. Lancet. 1971 May 8;1(7706):975–976. doi: 10.1016/s0140-6736(71)91484-x. [DOI] [PubMed] [Google Scholar]
- Schwartz G. J., Haycock G. B., Edelmann C. M., Jr, Spitzer A. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics. 1976 Aug;58(2):259–263. [PubMed] [Google Scholar]