Abstract
The management and outcome of 242 infants delivered between 26 and 34 weeks' gestation in an obstetrical and neonatal regional referral centre as a result of spontaneous preterm labour were recorded prospectively. Results of the survey show that the decision to intervene and delay delivery will depend on the availability of neonatal intensive care facilities. Infants likely to require intensive neonatal care should be transferred in utero to a centre with these facilities. The use of steroids reduces the mortality of preterm infants. The maximum effect occurs between 30 and 32 weeks' gestation, and there is no benefit after 34 weeks. If the weight is over 1500 g the mode of delivery of the preterm infant presenting by the breech does not influence outcome; if under 1500 g a caesarean section improves survival over those infants born by vaginal breech delivery.
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Selected References
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- Ballard P. L., Ballard R. A., Granberg J. P., Sniderman S., Gluckman P. D., Kaplan S. L., Grumbach M. M. Fetal sex and prenatal betamethasone therapy. J Pediatr. 1980 Sep;97(3):451–454. doi: 10.1016/s0022-3476(80)80204-6. [DOI] [PubMed] [Google Scholar]
- Ballard R. A., Ballard P. L. Use of prenatal glucocorticoid therapy to prevent respiratory distress syndrome. A supporting view. Am J Dis Child. 1976 Sep;130(9):982–987. doi: 10.1001/archpedi.1976.02120100072011. [DOI] [PubMed] [Google Scholar]
- Caspi E., Schreyer P., Weinraub Z., Lifshitz Y., Goldberg M. Dexamethasone for prevention of respiratory distress syndrome: multiple perinatal factors. Obstet Gynecol. 1981 Jan;57(1):41–47. [PubMed] [Google Scholar]
- Hobbins J. C., Grannum P. A., Berkowitz R. L., Silverman R., Mahoney M. J. Ultrasound in the diagnosis of congenital anomalies. Am J Obstet Gynecol. 1979 Jun 1;134(3):331–345. doi: 10.1016/s0002-9378(16)33043-5. [DOI] [PubMed] [Google Scholar]
- Levene M. I., Fawer C. L., Lamont R. F. Risk factors in the development of intraventricular haemorrhage in the preterm neonate. Arch Dis Child. 1982 Jun;57(6):410–417. doi: 10.1136/adc.57.6.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Levene M. I., Wigglesworth J. S., Dubowitz V. Cerebral structure and intraventricular haemorrhage in the neonate: a real-time ultrasound study. Arch Dis Child. 1981 Jun;56(6):416–424. doi: 10.1136/adc.56.6.416. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lewis P. J., de Swiet M., Boylan P., Bulpitt C. J. How obstetricians in the United Kingdom manage preterm labour. Br J Obstet Gynaecol. 1980 Jul;87(7):574–577. doi: 10.1111/j.1471-0528.1980.tb05006.x. [DOI] [PubMed] [Google Scholar]
- Liggins G. C., Howie R. N. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics. 1972 Oct;50(4):515–525. [PubMed] [Google Scholar]
- Martin C. B., Jr, Siassi B., Hon E. H. Fetal heart rate patterns and neonatal death in low birthweight infants. Obstet Gynecol. 1974 Oct;44(4):503–510. [PubMed] [Google Scholar]
- Merkatz I. R., Peter J. B., Barden T. P. Ritodrine hydrochloride: a betamimetic agent for use in preterm labor. II. Evidence of efficacy. Obstet Gynecol. 1980 Jul;56(1):7–12. [PubMed] [Google Scholar]
- Taeusch H. W., Jr, Frigoletto F., Kitzmiller J., Avery M. E., Hehre A., Fromm B., Lawson E., Neff R. K. Risk of respiratory distress syndrome after prenatal dexamethasone treatment. Pediatrics. 1979 Jan;63(1):64–72. [PubMed] [Google Scholar]
- Warsof S. L., Gohari P., Berkowitz R. L., Hobbins J. C. The estimation of fetal weight by computer-assisted analysis. Am J Obstet Gynecol. 1977 Aug 15;128(8):881–892. doi: 10.1016/0002-9378(77)90058-8. [DOI] [PubMed] [Google Scholar]
- Whittle M. J., Wilson A. I., Whitfield C. R., Paton R. D., Logan R. W. Amniotic fluid phospholipid profile determined by two-dimensional thin-layer chromatography as index of fetal lung maturation. Br Med J (Clin Res Ed) 1981 Feb 7;282(6262):428–430. doi: 10.1136/bmj.282.6262.428. [DOI] [PMC free article] [PubMed] [Google Scholar]
