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British Medical Journal (Clinical Research Ed.) logoLink to British Medical Journal (Clinical Research Ed.)
. 1983 Mar 5;286(6367):755–758. doi: 10.1136/bmj.286.6367.755

Endoscopic review of patients who have had gastric surgery.

P A Farrands, J R Blake, I D Ansell, R E Cotton, J D Hardcastle
PMCID: PMC1547018  PMID: 6402234

Abstract

Seventy one patients who had had operations on their stomachs over 15 years previously were examined by endoscopy and multiple mucosal biopsy sampling. Sixty six had histologically proved gastritis (56 chronic atrophic gastritis, 10 superficial gastritis), 38 intestinal metaplasia, and 11 epithelial dysplasia. In three cases the epithelial dysplasia was severe (carcinoma in situ). One patient had an infiltrating carcinoma and another, whose biopsy appearances were reported as severe dysplasia, developed a carcinoma of the stomach eight months later. All patients having undergone gastric surgery more than five years previously should be screened endoscopically and any found to have moderate dysplasia subjected to regular endoscopic screening thereafter. Patients with severe dysplasia (carcinoma in situ) should be considered for radical surgery.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cuello C., López J., Correa P., Murray J., Zarama G., Gordillo G. Histopathology of gastric dysplasias: correlations with gastric juice chemistry. Am J Surg Pathol. 1979 Dec;3(6):491–500. doi: 10.1097/00000478-197912000-00002. [DOI] [PubMed] [Google Scholar]
  2. Domellöf L., Janunger K. G. The risk for gastric carcinoma after partial gastrectomy. Am J Surg. 1977 Nov;134(5):581–584. doi: 10.1016/0002-9610(77)90439-1. [DOI] [PubMed] [Google Scholar]
  3. Eberlein T. J., Lorenzo F. V., Webster M. W. Gastric carcinoma following operation for peptic ulcer disease. Ann Surg. 1978 Mar;187(3):251–256. doi: 10.1097/00000658-197803000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. HELSINGEN N., HILLESTAD L. Cancer development in the gastric stump after partial gastrectomy for ulcer. Ann Surg. 1956 Feb;143(2):173–179. doi: 10.1097/00000658-195614320-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Husian O. A. Cytological screening for cancer of the stomach. Proc R Soc Med. 1976 Jul;69(7):489–494. [PMC free article] [PubMed] [Google Scholar]
  6. Keighley M. R., Thompson H., Moore J., Hoare A. M., Allan R. N., Dykes P. W. Comparison of brush cytology before or after biopsy for diagnosis of gastric carcinoma. Br J Surg. 1979 Apr;66(4):246–247. doi: 10.1002/bjs.1800660408. [DOI] [PubMed] [Google Scholar]
  7. LIAVAAG K. Cancer development in gastric stump after partial gastrectomy for peptic ulcer. Ann Surg. 1962 Jan;155:103–106. doi: 10.1097/00000658-196201000-00012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lambert R. Chronic gastritis. A critical study of the progressive atrophy of the gastric mucosa. Digestion. 1972;7(1):83–126. doi: 10.1159/000197264. [DOI] [PubMed] [Google Scholar]
  9. Morgenstern L., Yamakawa T., Seltzer D. Carcinoma of the gastric stump. Am J Surg. 1973 Jan;125(1):29–38. doi: 10.1016/0002-9610(73)90005-6. [DOI] [PubMed] [Google Scholar]
  10. Morson B. C., Sobin L. H., Grundmann E., Johansen A., Nagayo T., Serck-Hanssen A. Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol. 1980 Aug;33(8):711–721. doi: 10.1136/jcp.33.8.711. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Oehlert W., Keller P., Henke M., Strauch M. Gastric mucosal dysplasia: what is its clinical significance? Front Gastrointest Res. 1979;4:173–182. doi: 10.1159/000402299. [DOI] [PubMed] [Google Scholar]
  12. Papachristou D. N., Agnanti N., Fortner J. G. Gastric carcinoma after treatment of ulcer. Am J Surg. 1980 Feb;139(2):193–196. doi: 10.1016/0002-9610(80)90252-4. [DOI] [PubMed] [Google Scholar]
  13. Rakovec S., Kovic M. Predisposition of the resected stomach for malignancy. World J Surg. 1981 Sep;5(5):725–727. doi: 10.1007/BF01657937. [DOI] [PubMed] [Google Scholar]
  14. Reynolds K. W., Johnson A. G., Fox B. Is intestinal metaplasia of the gastric mucosa a pre-malignant lesion? Clin Oncol. 1975 Jun;1(2):101–109. [PubMed] [Google Scholar]
  15. Savage A., Jones S. Histological appearances of the gastric mucosa 15--27 years after partial gastrectomy. J Clin Pathol. 1979 Feb;32(2):179–186. doi: 10.1136/jcp.32.2.179. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Schrumpf E., Serck-Hanssen A., Stadaas J., Aune S., Myren J., Osnes M. Mucosal changes in the gastric stump 20-25 years after partial gastrectomy. Lancet. 1977 Sep 3;2(8036):467–469. doi: 10.1016/s0140-6736(77)91599-9. [DOI] [PubMed] [Google Scholar]
  17. Siurala M., Isokoski M., Varis K., Kekki M. Prevalence of gastritis in a rural population. Bioptic study of subjects selected at random. Scand J Gastroenterol. 1968;3(2):211–223. doi: 10.3109/00365526809180125. [DOI] [PubMed] [Google Scholar]
  18. Siurala M., Lehtola J., Ihamäki T. Atrophic gastritis and its sequelae. Results of 19-23 years' follow-up examinations. Scand J Gastroenterol. 1974;9(5):441–446. [PubMed] [Google Scholar]
  19. Smithies A., Lovell D., Hishon S., Kellock T. D., Mislewicz J. J., Newton C., Pounder R. E., Blendis L. M. Proceedings: The value of brush cytology in the diagnosis of gastric cancer. Gut. 1975 May;16(5):395–395. [PubMed] [Google Scholar]
  20. Stalsberg H., Taksdal S. Stomach cancer following gastric surgery for benign conditions. Lancet. 1971 Nov 27;2(7735):1175–1177. doi: 10.1016/s0140-6736(71)90489-2. [DOI] [PubMed] [Google Scholar]
  21. Young J. A., Hughes H. E., Lee F. D. Evaluation of endoscopic brush and biopsy touch smear cytology and biopsy histology in the diagnosis of carcinoma of the lower oesophagus and cardia. J Clin Pathol. 1980 Sep;33(9):811–814. doi: 10.1136/jcp.33.9.811. [DOI] [PMC free article] [PubMed] [Google Scholar]

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