Abstract
The effect of environment on blood pressure was studied by recording intra-arterial pressure continuously in nine patients with essential hypertension during controlled periods of activity and rest at home and in hospital. Mean systolic pressure was higher at home (152 +/- 16 mm Hg) than in hospital (138 +/- 11 mm Hg, p less than 0.01), the difference being greatest during the period of activity (165 +/- 21 v 142 +/- 13 mm Hg, p less than 0.001); heart rates and diastolic pressures did not differ significantly at these times. Systolic pressure recorded by conventional sphygmomanometry was also higher at home (173 +/- 23 v 159 +/- 23 mm Hg, p less than 0.01), as was diastolic pressure (98 +/- 10 v 89 +/- 11 mm Hg, p less than 0.02). Systolic pressure was consistently higher at home, and this effect was independent of the pressure of an observer. This must be taken into consideration when assessing blood pressure and efficacy of treatment in hospital.
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Selected References
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- Brennan P. J., Greenberg G., Miall W. E., Thompson S. G. Seasonal variation in arterial blood pressure. Br Med J (Clin Res Ed) 1982 Oct 2;285(6346):919–923. doi: 10.1136/bmj.285.6346.919. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hecht K., Hecht T., Treptow K. Bezienhungen zwischen Funktionszustand des ZNS und dem konditionierten pharmakologischen Effekt. Ein Beitrag zum Plazebo-Effekt. Acta Biol Med Ger. 1968;20(6):773–785. [PubMed] [Google Scholar]
- Hossmann V., FitzGerald G. A., Dollery C. T. Influence of hospitalization and placebo therapy on blood pressure and sympathetic function in essential hypertension. Hypertension. 1981 Jan-Feb;3(1):113–118. doi: 10.1161/01.hyp.3.1.113. [DOI] [PubMed] [Google Scholar]
- Julius S., Ellis C. N., Pascual A. V., Matice M., Hansson L., Hunyor S. N., Sandler L. N. Home blood pressure determination. Value in borderline ("labile") hypertension. JAMA. 1974 Aug 5;229(6):663–666. [PubMed] [Google Scholar]
- Laughlin K. D., Sherrard D. J., Fisher L. Comparison of clinic and home blood pressure levels in essential hypertension and variables associated with clinic-home differences. J Chronic Dis. 1980;33(4):197–206. doi: 10.1016/0021-9681(80)90064-8. [DOI] [PubMed] [Google Scholar]
- Med M. Prenatal development of lumbar intervertebral articulation. Folia Morphol (Praha) 1982;30(3):285–290. [PubMed] [Google Scholar]
- RICHARDSON D. W., HONOUR A. J., FENTON G. W., STOTT F. H., PICKERING G. W. VARIATION IN ARTERIAL PRESSURE THROUGHOUT THE DAY AND NIGHT. Clin Sci. 1964 Jun;26:445–460. [PubMed] [Google Scholar]
- Watson R. D., Stallard T. J., Littler W. A. Influence of once-daily administration of beta-adrenoceptor antagonists on arterial pressure and its variability. Lancet. 1979 Jun 9;1(8128):1210–1213. doi: 10.1016/s0140-6736(79)91896-8. [DOI] [PubMed] [Google Scholar]