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. 1983 Apr 9;286(6372):1171–1172. doi: 10.1136/bmj.286.6372.1171

Diurnal variation of lymphocyte subsets identified by monoclonal antibodies.

J V Bertouch, P J Roberts-Thomson, J Bradley
PMCID: PMC1547388  PMID: 6220755

Abstract

Monoclonal antibodies specific for lymphocyte subsets were used to examine circulating lymphocytes obtained at frequent intervals from healthy subjects. A diurnal rhythm was found in the total numbers of lymphocytes, T cells, inducer/helper cells, suppressor/cytotoxic cells, Ia positive cells, and B cells. The lowest levels of all subsets were seen at 0900 hours and the highest levels at 2100. In some subjects the ratio of helper to suppressor cells varied considerably during the sample period, though the ratio was relatively constant for the group as a whole.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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