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. 1983 Nov 5;287(6402):1337–1338. doi: 10.1136/bmj.287.6402.1337

Sex hormones and skin collagen content in postmenopausal women.

M Brincat, C F Moniz, J W Studd, A J Darby, A Magos, D Cooper
PMCID: PMC1549492  PMID: 6416400

Abstract

Skin biopsy specimens were taken from 29 postmenopausal women who had not been given hormone replacement therapy and from 26 women who had been treated with oestrogen and testosterone implants for two to 10 years. The mean hydroxyproline content and therefore the mean collagen content in the skin was found to be 48% greater in the treated than the untreated women, who were matched for age. This difference was significant (p less than 0.01). The implication of this finding is that oestrogen or testosterone, or both, prevents the decrease in skin collagen content that occurs with aging and protects skin in the same way as it protects bone in postmenopausal women.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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