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. 1969 Nov;10(11):928–930. doi: 10.1136/gut.10.11.928

A comparison between the gastric and salivary concentration of iodide, pertechnetate, and bromide in man

R McG Harden, W D Alexander, J Shimmins, D Chisholm
PMCID: PMC1553065  PMID: 5358585

Abstract

The concentration of iodide (I−) and pertechnetate (TcO4−) and bromide (Br−) has been measured simultaneously in gastric juice and parotid saliva. The combined gastric and salivary clearance for iodide and pertechnetate is more than twice the clearance of these ions by the thyroid gland. The concentration of the ions was in the order I−>TcO4−>Br− in both gastric juice and saliva. Differences exist between the secretion of iodide, pertechnetate, and bromide. Bromide, in contrast to iodide and pertechnetate, was found to be more concentrated in gastric juice than in saliva. The ratio of the iodide to pertechnetate clearance was greater in gastric juice than in saliva.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDROS G., HARPER P. V., LATHROP K. A. PERTECHNETATE-99M LOCALIZATION IN MAN WITH APPLICATIONS TO THYROID SCANNING AND THE STUDY OF THYROID PHYSIOLOGY. J Clin Endocrinol Metab. 1965 Aug;25:1067–1076. doi: 10.1210/jcem-25-8-1067. [DOI] [PubMed] [Google Scholar]
  2. BROWN-GRANT K., CUMMING J. D., HAIGH A. L., HARRIES E. H. THE SECRETION OF RADIOACTIVE IODIDE BY THE STOMACH OF THE ANAESTHETIZED DOG IN RELATION TO TOTAL GASTRIC BLOOD FLOW AND TO ACID SECRETION. J Physiol. 1965 Apr;177:337–345. doi: 10.1113/jphysiol.1965.sp007595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. GAMBLE J. L., Jr, ROBERTSON J. S., HANNIGAN C. A., FOSTER C. G., FARR L. E. Chloride, bromide, sodium, and sucrose spaces in man. J Clin Invest. 1953 Jun;32(6):483–489. doi: 10.1172/JCI102764. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. HARDEN R. M., MASON D. K., BUCHANAN W. W. QUANTITATIVE STUDIES OF IODIDE EXCRETION IN SALIVA IN EUTHYROID, HYPOTHYROID AND THYROTOXIC PATIENTS. J Clin Endocrinol Metab. 1965 Jul;25:957–961. doi: 10.1210/jcem-25-7-957. [DOI] [PubMed] [Google Scholar]
  5. HONOUR A. J., MYANT N. B., ROWLANDS E. N. Secretion of radioiodine in digestive juices and milk in man. Clin Sci. 1952 Nov;11(4):449–462. [PubMed] [Google Scholar]
  6. Harden R. M., Alexander W. D., Shimmins J., Kostalas H., Mason D. K. Quantitative aspects of the inhibitory effect of the iodide ion on parotid salivary iodide and pertechnetate secretion in man. J Lab Clin Med. 1968 Jan;71(1):92–100. [PubMed] [Google Scholar]
  7. Harden R. M., Hilditch T. E., Kennedy I., Mason D. K., Papadopoulos S., Alexander W. D. Uptake and scanning of the salivary glands in man using pertechnetate-99m-Tc. Clin Sci. 1967 Feb;32(1):49–55. [PubMed] [Google Scholar]
  8. Harden R., Alexander W. D. Isotope uptake and scanning of stomach in man with 99mTc-pertechnetate. Lancet. 1967 Jun 17;1(7503):1305–1307. doi: 10.1016/s0140-6736(67)91597-8. [DOI] [PubMed] [Google Scholar]
  9. Herbert R., Kulke W., Shepherd R. T. The use of technetium 99m as a clinical tracer element. Postgrad Med J. 1965 Nov;41(481):656–662. doi: 10.1136/pgmj.41.481.656. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. ULLBERG S., APPELGREN L. E., CLEMEDSON C. J., ERICSSON Y., EWALDSSON B., SOERBO B., SOEREMARK R. A COMPARISON OF THE DISTRIBUTION OF SOME HALIDE IONS IN THE BODY. Biochem Pharmacol. 1964 Mar;13:407–412. doi: 10.1016/0006-2952(64)90160-1. [DOI] [PubMed] [Google Scholar]
  11. ULLBERG S., SOREMARK R. Autoradiographic localization of bromide (Br82 and Br80m) in the gastric mucosa. Gastroenterology. 1961 Jan;40:109–112. [PubMed] [Google Scholar]
  12. WOLFF J. TRANSPORT OF IODIDE AND OTHER ANIONS IN THE THYROID GLAND. Physiol Rev. 1964 Jan;44:45–90. doi: 10.1152/physrev.1964.44.1.45. [DOI] [PubMed] [Google Scholar]

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