Skip to main content
PMC home page
Gut logoLink to Gut
. 1970 Jul;11(7):588–591. doi: 10.1136/gut.11.7.588

Fibrinolysis in colonic disease

C H J Swan, J Alexander Williams, W T Cooke
PMCID: PMC1553073  PMID: 5452047

Abstract

Fibrinolytic activity of colic venous and arterial blood has been studied at laparotomy in 18 patients with ulcerative colitis or Crohn's colitis and compared with that of 17 patients with colonic carcinoma or diverticulosis. Using the dilute blood clot lysis time technique, no difference was detected between the fibrinolytic activity in colic venous blood from the two groups. When the clinical complications of bleeding or thrombosis are compared with fibrinolytic activity the only important association is between a low peripheral venous fibrinolytic activity and the occurrence of postoperative thrombo-embolic complications.

Full text

PDF
588

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALBRECHTSEN O. K. The fibrinolytic activity of human tissues. Br J Haematol. 1957 Jul;3(3):284–291. doi: 10.1111/j.1365-2141.1957.tb05798.x. [DOI] [PubMed] [Google Scholar]
  2. ALBRECHTSEN O. K. The fibrinolytic agents in saline extracts of human tissues. Scand J Clin Lab Invest. 1958;10(1):91–96. doi: 10.3109/00365515809079923. [DOI] [PubMed] [Google Scholar]
  3. ASTRUP T., ALBRECHTSEN O. K. Estimation of the plasminogen activator and the trypsin inhibitor in animal and human tissues. Scand J Clin Lab Invest. 1957;9(3):233–243. doi: 10.3109/00365515709079963. [DOI] [PubMed] [Google Scholar]
  4. ASTRUP T. The biological significance of fibrinolysis. Lancet. 1956 Sep 15;271(6942):565–568. doi: 10.1016/s0140-6736(56)92048-7. [DOI] [PubMed] [Google Scholar]
  5. Bennett N. B., Ogston C. M., McAndrew G. M. The thyroid and fibrinolysis. Br Med J. 1967 Oct 28;4(5572):147–148. doi: 10.1136/bmj.4.5572.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cox H. T., Poller L., Thomson J. M. Gastric fibrinolysis. A possible aetiological link with peptic ulcer. Lancet. 1967 Jun 17;1(7503):1300–1302. doi: 10.1016/s0140-6736(67)91594-2. [DOI] [PubMed] [Google Scholar]
  7. FEARNLEY G. R., BALMFORTH G., FEARNLEY E. Evidence of a diurnal fibrinolytic rhythm; with a simple method of measuring natural fibrinolysis. Clin Sci. 1957 Nov;16(4):645–650. [PubMed] [Google Scholar]
  8. FEARNLEY G. R., FERGUSON J. Arteriovenous difference in natural fibrinolysis. Lancet. 1957 Nov 23;273(7004):1040–1041. doi: 10.1016/s0140-6736(57)92157-8. [DOI] [PubMed] [Google Scholar]
  9. Holemans R., Mann L. S., Cope C. Fibrinolytic activity of renal venous and arterial blood. Am J Med Sci. 1967 Sep;254(3):330–333. doi: 10.1097/00000441-196709000-00008. [DOI] [PubMed] [Google Scholar]
  10. Kwaan H. C., Cocco A., Mendeloff A. I., Astrup T. Fibrinolytic activity in the normal and inflamed rectal mucosa. Scand J Gastroenterol. 1969;4(5):441–445. doi: 10.3109/00365526909180630. [DOI] [PubMed] [Google Scholar]
  11. MCNICOL G. P., DOUGLAS A. S. EPSILON-AMINOCAPROIC ACID AND OTHER INHIBITORS OF FIBRINOLYSIS. Br Med Bull. 1964 Sep;20:233–239. doi: 10.1093/oxfordjournals.bmb.a070338. [DOI] [PubMed] [Google Scholar]
  12. Mackay A. V., Das P. C., Myerscough P. R., Cash J. D. Fibrinolytic components of human uterine arterial and venous blood. J Clin Pathol. 1967 May;20(3):227–230. doi: 10.1136/jcp.20.3.227. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Sherry S. Fibrinolytic mechanisms in tissue injury. Gastroenterology. 1966 Nov;51(5):901–912. [PubMed] [Google Scholar]
  14. TODD A. S. Fibrinolysis autographs. Nature. 1958 Feb 15;181(4607):495–496. doi: 10.1038/181495b0. [DOI] [PubMed] [Google Scholar]
  15. TODD A. S. LOCALIZATION OF FIBRINOLYTIC ACTIVITY IN TISSUES. Br Med Bull. 1964 Sep;20:210–212. doi: 10.1093/oxfordjournals.bmb.a070333. [DOI] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES