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. 1972 Dec;12(4):429–438.

The effect of thyroid antigens on the in vitro migration of leucocytes from patients with Hashimoto thyroiditis

Elizabeth A Calder, Dena McLeman, E W Barnes, W J Irvine
PMCID: PMC1553603  PMID: 4568149

Abstract

A total of fifty-two patients with Hashimoto thyroiditis were tested for delayed hypersensitivity to thyroid antigens using the leucocyte migration test. The percentage of patients showing abnormal migration in the presence of crude thyroid extract, thyroglobulin, thyroid mitochondria and thyroid microsomes was 75, 44, 54 and 34% respectively. Fifty-three control patients were studied concurrently with the same antigens and the percentage showing abnormal migration was 4, 6, 6 and 6% respectively. The antigenic activity of the mitochondrial fraction was not organ specific; both liver and kidney mitochondria interfered with the migration of leucocytes from patients with Hashimoto thyroiditis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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