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. 1973 May;14(1):25–35.

Lymphocyte sensitivity to skeletal muscle in patients with polymyositis and other disorders

Margaret M Esiri, I C M Maclennan, B L Hazleman
PMCID: PMC1553848  PMID: 4716102

Abstract

The transformation response of peripheral blood lymphocytes in vitro to human muscle antigen has been studied in patients with polymyositis, polymyalgia rheumatica and rheumatoid arthritis. Lymphocytes from patients with polymyositis and polymyalgia rheumatica, but not rheumatoid arthritis, showed transformation responses significantly higher than those in control groups, and the highest responses were found in patients with evidence of the most active clinical disease at the time of testing. The significance of finding hypersensitivity to crude muscle antigen in both these conditions is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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