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. 1973 Sep;15(1):35–42.

Phytohaemagglutinin (PHA) induced lymphocyte transformation and toxoplasma gondii antibody studies in primary biliary cirrhosis. Evidence of impaired cell-mediated immunity

R N M Macsween, I Galbraith, Mair A Thomas, G Watkinson, G B Ludlam
PMCID: PMC1553872  PMID: 4765720

Abstract

Phytohaemagglutinin (PHA) induced dose-response lymphocyte transformation has been studied in a group of patients with primary biliary cirrhosis. There is a marked reduction in responsiveness, particularly with low doses of PHA. These observations, together with the finding of a raised incidence (7%) of high titre Toxoplasma gondii antibody in primary biliary cirrhosis patients, are adduced as evidence of impaired cell-mediated immunity in this disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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