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. 1974 May;17(1):159–167.

Inter-mouse strain differences in macrophage function and its relationship to antibody responses

J H Passwell, M W Steward, J F Soothill
PMCID: PMC1554062  PMID: 4282849

Abstract

Macrohage function, as measured by carbon clearance, differs in different inbred strains. Low affinity (KR) antibody response to HST is associated either with poor carbon clearance, or slow recovery from carbon blockade by macrophages.

Carbon blockade reduces KR, but not Abt in mice with high carbon clearance and KR.

Stilboestrol increases carbon clearance and KR in mice with slow clearance and low KR.

The significance of these findings in pathogenesis and treatment of chronic soluble complex disease is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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