Abstract
The addition of Tuberculin PPD to whole blood resulted in aggregation of the leucocytes. The degree of aggregation was assessed macroscopically and by two microscopic methods. The dose of PPD required to produce aggregation varied greatly between different subjects and an inverse correlation was noted between the dose of PPD needed and the Mantoux reaction.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Crowther D., Powles R. L., Bateman C. J., Beard M. E., Gauci C. L., Wrigley P. F., Malpas J. S., Fairley G. H., Scott R. B. Management of adult acute myelogenous leukaemia. Br Med J. 1973 Jan 20;1(5846):131–137. doi: 10.1136/bmj.1.5846.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DAVID J. R., AL-ASKARI S., LAWRENCE H. S., THOMAS L. DELAYED HYPERSENSITIVITY IN VITRO. I. THE SPECIFICITY OF INHIBITION OF CELL MIGRATION BY ANTIGENS. J Immunol. 1964 Aug;93:264–273. [PubMed] [Google Scholar]
- Gotoff S. P., Vizral I. F. The macrophage aggregation assay for delayed hypersensitivity: development of the response, role of the macrophage, and the independence of humoral antibody. Cell Immunol. 1972 Jan;3(1):53–61. doi: 10.1016/0008-8749(72)90225-0. [DOI] [PubMed] [Google Scholar]
- NELSON D. S., NORTH R. J. THE FATE OF PERITONEAL MACROPHAGES AFTER THE INJECTION OF ANTIGEN INTO GUINEA PIGS WITH DELAYED-TYPE HYPERSENSITIVITY. Lab Invest. 1965 Jan;14:89–101. [PubMed] [Google Scholar]
- Ward P. A., Remold H. G., David J. R. The production by antigen-stimulated lymphocytes of a leukotactic factor distinct from migration inhibitory factor. Cell Immunol. 1970 Jul;1(2):162–174. doi: 10.1016/0008-8749(70)90003-1. [DOI] [PubMed] [Google Scholar]