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. 1992 May;88(2):237–242. doi: 10.1111/j.1365-2249.1992.tb03067.x

Prolonged clinically asymptomatic evolution after HIV-1 infection is marked by the absence of complement C4 null alleles at the MHC.

F Hentges 1, A Hoffmann 1, F Oliveira de Araujo 1, R Hemmer 1
PMCID: PMC1554293  PMID: 1572087

Abstract

The length of time after which persons infected with HIV-1 progress to AIDS is variable. Certain alleles at the MHC have been shown to influence negatively the clinical outcome of HIV-1-infected persons and to be associated with special clinical manifestations. We investigated the MHC class I, class II and class III antigens in 54 Caucasian HIV-1-infected persons. The MHC profile of individuals with a prolonged period before AIDS is marked by a lower frequency of C4 null alleles.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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