Jonathan Leo raises issues with the adoption literature on schizophrenia [1]. These studies were intensively and independently scrutinized in the 1980s—see the series of papers by Kendler and Gruenberg (e.g., [2]). Most would agree that the number, size, and quality of adoption studies do not provide the highest-quality data (as discussed at more length elsewhere [3].
However, the salient point in my paper [4] was that this body of work (twin, adoption, and family studies) provides a consistent and solid rationale for the search for genes for schizophrenia.
Dr. Leo's comments about the treatment of schizophrenia are not within the scope of my paper.
Footnotes
Funding: The author received no specific funding for this article.
Competing Interests: The author has declared that no competing interests exist.
References
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