Abstract
In this paper, a generalized logistic regression model for correlated observations is used to analyze epidemiologic data on the frequency of spontaneous abortion among a group of women office workers. The results are compared to those obtained from the use of the standard logistic regression model that assumes statistical independence among all the pregnancies contributed by one woman. In this example, the correlation among pregnancies from the same woman is fairly small and did not have a substantial impact on the magnitude of estimates of parameters of the model. This is due at least partly to the small average number of pregnancies contributed by each woman.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chinchilli V. M., Clark B. C. Trend tests for proportional responses in developmental toxicity experiments. Environ Health Perspect. 1989 Feb;79:217–221. doi: 10.1289/ehp.8979217. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Haseman J. K., Kupper L. L. Analysis of dichotomous response data from certain toxicological experiments. Biometrics. 1979 Mar;35(1):281–293. [PubMed] [Google Scholar]
- Levine R. J., Symons M. J., Balogh S. A., Arndt D. M., Kaswandik N. T., Gentile J. W. A method for monitoring the fertility of workers. 1. Method and pilot studies. J Occup Med. 1980 Dec;22(12):781–791. doi: 10.1097/00043764-198012000-00011. [DOI] [PubMed] [Google Scholar]
- Rosner B. Multivariate methods in ophthalmology with application to other paired-data situations. Biometrics. 1984 Dec;40(4):1025–1035. [PubMed] [Google Scholar]
- Williams D. A. The analysis of binary responses from toxicological experiments involving reproduction and teratogenicity. Biometrics. 1975 Dec;31(4):949–952. [PubMed] [Google Scholar]
