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. 1989 Jul;82:311–321. doi: 10.1289/ehp.82-1568111

Trends and perspectives of the biological prophylaxis of silicosis.

B A Katsnelson 1, E V Polzik 1, K I Morosova 1, L I Privalova 1, Kochneva MYu 1, N S Kislitsina 1, V S Kasantsev 1
PMCID: PMC1568111  PMID: 2676501

Abstract

Based on earlier paper in this journal, as well as on new data concerning factors predetermining individual susceptibility to silicosis, we propose a comprehensive system of recommendations aimed at increasing the working population's resistance against the harmful action of silica dust. These recommendations consider, on one hand, the criteria of possible selection for employment in dusty industries of individuals who do not possess characteristics making them especially sensitive to this harmful action (collective biological prophylaxis), and on the other hand, the influences that could diminish such sensitivity (individual biological prophylaxis). Some ethical and practical problems of the biological prophylaxis of occupational diseases and a mathematical approach to predicting its effectiveness are also discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Babushkina L. G., Katsnel'son B. A., Kisklitsina N. S. O vozdeistvii antioksidantov na narusheniia lipidnogo obmena i fibrogenez v legochnoi tkani pri éksperimental'nom silikoze. Vopr Med Khim. 1981;27(4):466–469. [PubMed] [Google Scholar]
  2. Babushkina L. G., Rusiaeva L. V. Vliianie zhirovoi nagruzki na razvitie silikoza. Vopr Med Khim. 1976 Sep-Oct;22(5):678–683. [PubMed] [Google Scholar]
  3. Babushkina L. G. Vliianie dlitel'nogo kormleniia krys razlichnymi zhirami na razvitie soedinitel'noi tkani v legkikh i pecheni pri éksperimental'nom silikoze. Gig Sanit. 1974 Jul;(7):28–34. [PubMed] [Google Scholar]
  4. Chvapil M., Hurych J. Control of collagen biosynthesis. Int Rev Connect Tissue Res. 1968;4:67–196. doi: 10.1016/b978-1-4831-6754-1.50010-8. [DOI] [PubMed] [Google Scholar]
  5. Evans C. C., Lewinsöhn H. C., Evans J. M. Frequency of HLA antigen in asbestos workers with and without pulmonary fibrosis. Br Med J. 1977 Mar 5;1(6061):603–605. doi: 10.1136/bmj.1.6061.603. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Gabor S., Anca Z., Zugravu E. In vitro action of quartz on alveolar macrophage lipid peroxides. Arch Environ Health. 1975 Oct;30(10):499–501. doi: 10.1080/00039896.1975.10666761. [DOI] [PubMed] [Google Scholar]
  7. Gregor A., Singh S., Turner-Warwick M., Lawler S., Parkes W. R. The role of histocompatibility (HLA) antigens in asbestosis. Br J Dis Chest. 1979 Jul;73(3):245–252. [PubMed] [Google Scholar]
  8. Heise E. R., Mentnech M. S., Olenchock S. A., Kutz S. A., Morgan W. K., Merchant J. A., Major P. C. HLA-A1 and coalworkers' pneumoconiosis. Am Rev Respir Dis. 1979 Jun;119(6):903–908. doi: 10.1164/arrd.1979.119.6.903. [DOI] [PubMed] [Google Scholar]
  9. Huuskonen M. S., Tiilikainen A., Alanko K. HLA-B18 antigens and protection from pulmonary fibrosis in asbestos workers. Br J Dis Chest. 1979 Jul;73(3):253–259. [PubMed] [Google Scholar]
  10. Katsnelson B. A., Polzik E. V., Privalova L. I. Some aspects of the problem of individual predisposition to silicosis. Environ Health Perspect. 1986 Sep;68:175–185. doi: 10.1289/ehp.8668175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Katsnelson B. A., Privalova L. I., Kislitsina N. S., Podgaiko G. A. Correlation between cytotoxicity and fibrogenicity of silicosis-inducing dusts. Med Lav. 1984 Nov-Dec;75(6):450–462. [PubMed] [Google Scholar]
  12. Katsnelson B. A., Privalova L. I. Recruitment of phagocytizing cells into the respiratory tract as a response to the cytotoxic action of deposited particles. Environ Health Perspect. 1984 Apr;55:313–325. doi: 10.1289/ehp.8455313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Kharitonov R. A., Kozlova A. I. Issledovanie dermatologicheskikh priznakov dlia diagnostiki i prognoza épilepsii. Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(6):861–867. [PubMed] [Google Scholar]
  14. Koskinen H., Tiilikainen A., Nordman H. Increased prevalence of HLA-Aw19 and of the phenogroup Aw19,B18 in advanced silicosis. Chest. 1983 Jun;83(6):848–852. doi: 10.1378/chest.83.6.848. [DOI] [PubMed] [Google Scholar]
  15. Matej H., Lange A., Garncarek D., Smolik R., Roszak E. HLA and antinuclear antibody incidence in asbestos workers. Arch Immunol Ther Exp (Warsz) 1978;26(1-6):201–205. [PubMed] [Google Scholar]
  16. Matej H., Lange A., Smolik R. HLA antigens in asbestosis. Arch Immunol Ther Exp (Warsz) 1977;25(4):489–491. [PubMed] [Google Scholar]
  17. Merchant J. A., Klouda P. T., Soutar C. A., Parkes W. R., Lawler S. D., Turner-Warwick M. The HL-A system in asbestos workers. Br Med J. 1975 Jan 25;1(5951):189–191. doi: 10.1136/bmj.1.5951.189. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Morosova K. I., Aronova G. V., Katsnelson B. A., Velichkovski B. T., Genkin A. M., Elnichnykh L. N., Privalova L. I. On the defensive action of glutamate against the cytotoxicity and fibrogenicity of quartz dust. Br J Ind Med. 1982 Aug;39(3):244–252. doi: 10.1136/oem.39.3.244. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Morosova K. I., Katsnelson B. A., Rotenberg YuS, Belobragina G. V. A further experimental study of the antisilicotic effect of glutamate. Br J Ind Med. 1984 Nov;41(4):518–525. doi: 10.1136/oem.41.4.518. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Pevnitskii L. A., Fedrunova V. S., Nazarova E. K., Levin A. I., Garkavenko O. S. Nekotorye immunogeneticheskie pokazateli pri silikoze. Gig Tr Prof Zabol. 1978 May;(5):52–54. [PubMed] [Google Scholar]
  21. Rodkina B. S. K voprosu o roli shchelochnoi fosfatazy i askorbinovoi kisloty v obrazovanii soedinitel'noi tkani pri eksperimental'nom pnevmokonioze. Patol Fiziol Eksp Ter. 1965 Mar-Apr;9(2):36–39. [PubMed] [Google Scholar]
  22. Samuels S. W. Medical surveillance: biological, social, and ethical parameters. J Occup Med. 1986 Aug;28(8):572–577. doi: 10.1097/00043764-198608000-00009. [DOI] [PubMed] [Google Scholar]
  23. Shmuter G. M., Izotova P. V., Maslenko A. A., Furman A. A., Sobolevskaia T. T. Gigienicheskaia otsenka élektrokhimicheskogo metoda obezzarazhivaniia vody serebrom. Gig Sanit. 1986 Dec;(12):10–12. [PubMed] [Google Scholar]
  24. Sluis-Cremer G. K., Maier G. HLA antigens of the A and B locus in relation to the development of silicosis. Br J Ind Med. 1984 Aug;41(3):417–418. doi: 10.1136/oem.41.3.417. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Soutar C. A., Coutts I., Parkes W. R., Dodi I. A., Gauld S., Castro J. E., Turner-Warwick M. Histocompatibility antigens in coal miners with pneumoconiosis. Br J Ind Med. 1983 Feb;40(1):34–38. doi: 10.1136/oem.40.1.34. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Starozhinskaia T. A., Zosimov A. N., Khodzitskaia V. K. Osobennosti dermatoglifiki u podrostkov, bol'nykh tuberkulezom legkikh. Vrach Delo. 1984 Jul;(7):47–49. [PubMed] [Google Scholar]
  27. Vergnaud M. C., Petiot J. F., Griveau A. M., Boulier A., Leménager J. Etude des relations entre le système HLA et l'apparition d'une fibrose asbestosique dans un groupe de travailleurs exposés à l'aminate. Poumon Coeur. 1983;39(6):283–286. [PubMed] [Google Scholar]
  28. Voitenko V. P., Poliukhov A. M. Poligennaia porogovaia model' i nekotorye aspekty fenogenetiki pal'tsevykh uzorov che oveka. Genetika. 1981;17(12):2204–2211. [PubMed] [Google Scholar]

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