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. 1981 Apr;38:35–37. doi: 10.1289/ehp.813835

Introductory remarks: environmental and endogenous hazards to the female reproductive system.

R L Butcher, R D Page
PMCID: PMC1568432  PMID: 6263608

Abstract

The toxic action of environmental chemicals on reproduction and the toxiclike effects of ovarian hormones have been shown by numerous investigators. Some toxic effects of environmental chemicals on reproduction are through their action on hormonal secretion. Such effects on the endocrine system could provide additional approaches to investigations of toxicity of compounds. A better understanding of interactions of environmental chemicals with the endocrine system is needed. Therefore, it becomes important for a greater exchange of information and more interaction between toxicologists and endocrinologists.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brawer J. R., Naftolin F., Martin J., Sonnenschein C. Effects of a single injection of estradiol valerate on the hypothalamic arcuate nucleus and on reproductive function in the female rat. Endocrinology. 1978 Aug;103(2):501–512. doi: 10.1210/endo-103-2-501. [DOI] [PubMed] [Google Scholar]
  2. Brawer J. R., Schipper H., Naftolin F. Ovary-dependent degeneration in the hypothalamic arcuate nucleus. Endocrinology. 1980 Jul;107(1):274–279. doi: 10.1210/endo-107-1-274. [DOI] [PubMed] [Google Scholar]
  3. Butcher R. L., Collins W. E., Fugo N. W. Altered secretion of gonadotropins and steroids resulting from delayed ovulation in the rat. Endocrinology. 1975 Mar;96(3):576–586. doi: 10.1210/endo-96-3-576. [DOI] [PubMed] [Google Scholar]
  4. Butcher R. L., Pope R. S. Role of estrogen during prolonged estrous cycles of the rat on subsequent embryonic death or development. Biol Reprod. 1979 Sep;21(2):491–495. doi: 10.1095/biolreprod21.2.491. [DOI] [PubMed] [Google Scholar]
  5. Longo L. D. Environmental pollution and pregnancy: risks and uncertainties for the fetus and infant. Am J Obstet Gynecol. 1980 May 15;137(2):162–173. doi: 10.1016/0002-9378(80)90770-x. [DOI] [PubMed] [Google Scholar]
  6. McCormack K. M., Melrose P., Rickert D. E., Dent J. G., Gibson J. E., Hook J. B. Concomitant dietary exposure to polychlorinated biphenyls and polybrominated biphenyls: tissue distribution and arylhydrocarbon hydroxylase activity in lactating rats. Toxicol Appl Pharmacol. 1979 Jan;47(1):95–104. doi: 10.1016/0041-008x(79)90076-0. [DOI] [PubMed] [Google Scholar]
  7. Sullivan F. M., Barlow S. M. Congenital malformations and other reproductive hazards from environmental chemicals. Proc R Soc Lond B Biol Sci. 1979 Jul 18;205(1158):91–110. doi: 10.1098/rspb.1979.0051. [DOI] [PubMed] [Google Scholar]

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