Group-averaged event-related HDRs to smoking and control cues following overnight abstinence (Abstinent) and smoking as usual (Satiated) in dependent smokers. Values are expressed as percent signal change from baseline for the following regions: IFG, MFG, SFG, ventral ACG (V-ACG), dorsal ACG (D-ACG), ventral striatum (V-STR), thalamus (THL), and insula (INS). aObserved effects of Session in MFG and Stimulus in V-STR were only marginally significant (see Table 1 for statistical information).