Abstract
Paraneoplastic eosinophilia is reported in dogs, cats, and humans. Hypereosinophilia (an eosinophil count greater than 1.5 x 10(9) L) is often associated with metastasis and a poor prognosis. This report describes a case of paraneoplastic hypereosinophilia in a pony. Neoplasia should be included in the differential diagnoses in a horse with eosinophilia.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bailey M., Martin S. C., Lloyd S. Immunologic and hematologic responses in ponies with experimentally induced Strongylus vulgaris infection. Am J Vet Res. 1989 Aug;50(8):1386–1391. [PubMed] [Google Scholar]
- Bienzle D., Hughson S. L., Vernau W. Acute myelomonocytic leukemia in a horse. Can Vet J. 1993 Jan;34(1):36–37. [PMC free article] [PubMed] [Google Scholar]
- Frustaci A., Abdulla A. K., Possati G., Manzoli U. Persisting hypereosinophilia and myocardial activity in the fibrotic stage of endomyocardial disease. Chest. 1989 Sep;96(3):674–675. doi: 10.1378/chest.96.3.674. [DOI] [PubMed] [Google Scholar]
- Gabbas A. G., Li C. Y. Acute nonlymphocytic leukemia with eosinophilic differentiation. Am J Hematol. 1986 Jan;21(1):29–38. doi: 10.1002/ajh.2830210105. [DOI] [PubMed] [Google Scholar]
- Haldane J. H., Kapoor H., Morris J. Severe eosinophilia associated with a malignant islet cell tumour. CMAJ. 1989 May 1;140(9):1061–1063. [PMC free article] [PubMed] [Google Scholar]
- Hosoda M., Makino S., Kawabe T., Maeda Y., Satoh S., Takami M., Mayumi M., Arai K., Saitoh H., Yodoi J. Differential regulation of the low affinity Fc receptor for IgE (Fc epsilon R2/CD23) and the IL-2 receptor (Tac/p55) on eosinophilic leukemia cell line (EoL-1 and EoL-3). J Immunol. 1989 Jul 1;143(1):147–152. [PubMed] [Google Scholar]
- Mahmoud A. A., Stone M. K., Kellermeyer R. W. Eosinophilopoietin. A circulating low molecular weight peptide-like substance which stimulates the production of eosinophils in mice. J Clin Invest. 1977 Sep;60(3):675–682. doi: 10.1172/JCI108819. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morris D. D., Bloom J. C., Roby K. A., Woods K., Tablin F. Eosinophilic myeloproliferative disorder in a horse. J Am Vet Med Assoc. 1984 Nov 1;185(9):993–996. [PubMed] [Google Scholar]
- Samoszuk M., Nansen L. Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia. Blood. 1990 Jan 1;75(1):13–16. [PubMed] [Google Scholar]
- Sellon R. K., Rottman J. B., Jordan H. L., Wells M. R., Simpson R. M., Nelson P., Keene B. W. Hypereosinophilia associated with transitional cell carcinoma in a cat. J Am Vet Med Assoc. 1992 Aug 15;201(4):591–593. [PubMed] [Google Scholar]
- Silberstein D. S., Schoof D. D., Rodrick M. L., Tai P. C., Spry C. J., David J. R., Eberlein T. J. Activation of eosinophils in cancer patients treated with IL-2 and IL-2-generated lymphokine-activated killer cells. J Immunol. 1989 Mar 15;142(6):2162–2167. [PubMed] [Google Scholar]
- Silver R. M., Heyes M. P., Maize J. C., Quearry B., Vionnet-Fuasset M., Sternberg E. M. Scleroderma, fasciitis, and eosinophilia associated with the ingestion of tryptophan. N Engl J Med. 1990 Mar 29;322(13):874–881. doi: 10.1056/NEJM199003293221302. [DOI] [PubMed] [Google Scholar]
- Yamaguchi Y., Hayashi Y., Sugama Y., Miura Y., Kasahara T., Kitamura S., Torisu M., Mita S., Tominaga A., Takatsu K. Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. J Exp Med. 1988 May 1;167(5):1737–1742. doi: 10.1084/jem.167.5.1737. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yanagisawa K., Fukuoka T., Fujita S. Evidence for the neoplastic involvement of monocytic, eosinophilic and basophilic lineages in acute myelomonocytic leukemia with eosinophilia. Acta Haematol. 1990;83(3):145–148. doi: 10.1159/000205192. [DOI] [PubMed] [Google Scholar]