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. 1985 Jan;59(1):85–90.

Natural killer cell activity in asthma.

T Timonen, B Stenius-Aarniala
PMCID: PMC1577172  PMID: 3971600

Abstract

Peripheral blood natural killer (NK) activity was analysed from 32 asthma patients and 13 control donors. Male patients and female patients with atopic asthma had significantly stronger NK activity against the leukaemic cell line K-562. Fractionation of patient mononuclear cells by discontinuous density gradient centrifugation suggested that large granular lymphocytes (LGL) were the main mediators of the NK activity in asthmatics. Based on the lytic unit calculations, the strong NK activity in asthmatics is mainly due to increased frequency of LGL in peripheral blood rather than activity of individual NK cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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