Skip to main content
Clinical and Experimental Immunology logoLink to Clinical and Experimental Immunology
. 1969 Oct;5(4):365–370.

Circulating antibodies to corneal tissue in a patient suffering from Mooren's ulcer (ulcus rodens corneae)

O L Schaap, T E W Feltkamp, A C Breebaart
PMCID: PMC1579120  PMID: 4902502

Abstract

Autoantibodies to human corneal epithelium were demonstrated by the immunofluorescent technique in the serum of a patient suffering from ulcus rodens corneae (Mooren's ulcer). These antibodies were demonstrated in serum obtained before lamellar keratoplasty, and in samples taken 1½ and 4 years, respectively, after operation, when the process had reached the terminal stage. No antibodies fixed in vivo were demonstrated in the patient's own corneal tissue using the direct immunofluorescent technique.

However, in the serum of three other patients suffering from the same disease no antibodies could be demonstrated. Two of these sera were from patients who had undergone keratoplasty.

Full text

PDF
365

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. NELKEN D., NELKEN E. The serological specificity of the cornea. Immunology. 1962 Sep;5:595–602. [PMC free article] [PubMed] [Google Scholar]

Articles from Clinical and Experimental Immunology are provided here courtesy of British Society for Immunology

RESOURCES