Abstract
A patient with pulmonary tuberculosis developed jaundice and manifestations of generalized allergic reaction while receiving combined treatment with streptomycin, p-aminosalicylate and isonicotinic acid hydrazide. Amongst various tests for allergy, the lymphocyte transformation test provided evidence of allergy to isonicotinic acid hydrazide. Follow-up suggested successful `desensitization', and plasma glutamic oxaloacetic transaminase showed only a temporary tendency to rise whilst desensitization was being carried out.
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