Abstract
Increased sensitivity of the fluorescent antibody procedure was achieved by modification of the method employed. Specimens collected from experimentally infected laboratory animals and naturally infected domestic and wild animals were examined by means of this method. The results compared very favorably with those obtained by other investigators who used serological, cultural, animal inoculation and silver impregnation procedures on the same specimens.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- BABUDIERI B. Laboratory diagnosis of leptospirosis. Bull World Health Organ. 1961;24:45–58. [PMC free article] [PubMed] [Google Scholar]
- Boulanger P., Robertson A. Fluorescein-Labelled Antibody Technique for the Demonstration of Leptospira Pomona. Can J Comp Med Vet Sci. 1961 Dec;25(12):299–306. [PMC free article] [PubMed] [Google Scholar]
- DEACON W. E., FREEMAN E. M., HARRIS A. Fluorescent treponemal antibody test. Modification based on quantitation (FTA-200). Proc Soc Exp Biol Med. 1960 Apr;103:827–829. doi: 10.3181/00379727-103-25685. [DOI] [PubMed] [Google Scholar]
- MOULTON J. E., HOWARTH J. A. The demonstration of Leptospira canicola in hamster kidneys by means of fluorescent antibody. Cornell Vet. 1957 Oct;47(4):524–532. [PubMed] [Google Scholar]
- SHELDON W. H. Leptospiral antigen demonstrated by the fluorescent antibody technic in human muscle lesions of Leptospirosis icterohemorrhagiae. Proc Soc Exp Biol Med. 1953 Oct;84(1):165–167. doi: 10.3181/00379727-84-20578. [DOI] [PubMed] [Google Scholar]
- SMITH C. W., MARSHALL J. D., Jr, EVELAND W. C. Use of contrasting fluorescent dye as counterstain in fixed tissue preparations. Proc Soc Exp Biol Med. 1959 Oct;102:179–181. doi: 10.3181/00379727-102-25182. [DOI] [PubMed] [Google Scholar]
- WHITE F. H., RISTIC M. Detection of Leptospira pomona in guinea pig and bovine urine with fluorescein-labeled antibody. J Infect Dis. 1959 Sep-Oct;105:118–123. doi: 10.1093/infdis/105.2.118. [DOI] [PubMed] [Google Scholar]