Abstract
Pseudomonas aeruginosa was isolated from the sputum of 63 patients. In 34 the organism was a commensal, in 14 it was causing chronic suppuration, and in 10 had interfered with antibiotics directed against other organisms and was thus indirectly pathogenic. In five patients, all of whom died, the organism could have been acting as an acute pathogen. Attempts should be made to determine the nature of the organism's pathogenicity in a given patient and appropriate therapy withheld or administered accordingly.
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Selected References
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- Brown V. I., Lowbury E. J. Use of an improved cetrimide agar medium and other culture methods for Pseudomonas aeruginosa. J Clin Pathol. 1965 Nov;18(6):752–756. doi: 10.1136/jcp.18.6.752. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burns M. W., May J. R. Bacterial precipitins in serum of patients with cystic fibrosis. Lancet. 1968 Feb 10;1(7537):270–272. doi: 10.1016/s0140-6736(68)90121-9. [DOI] [PubMed] [Google Scholar]
- Burns M. W. The significance of various bacteria in chronic bronchial disorders as determined by bacterial antibody detection. Australas Ann Med. 1968 Nov;17(4):289–294. doi: 10.1111/imj.1968.17.4.289. [DOI] [PubMed] [Google Scholar]
- CALLAHAN W. S., BEYERLEIN B., MULL J. D. TOXICITY OF PSEUDOMONAS AERUGINOSA SLIME. J Bacteriol. 1964 Sep;88:805–806. doi: 10.1128/jb.88.3.805-806.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DOGGETT R. G., HARRISON G. M., STILLWELL R. N., WALLIS E. S. ENZYMATIC ACTION ON THE CAPSULAR MATERIAL PRODUCED BY PSEUDOMONAS AERUGINOSA OF CYSTIC FIBROSIS ORIGIN. J Bacteriol. 1965 Feb;89:476–480. doi: 10.1128/jb.89.2.476-480.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DOGGETT R. G., HARRISON G. M., WALLIS E. S. COMPARISON OF SOME PROPERTIES OF PSEUDOMONAS AERUGINOSA ISOLATED FROM INFECTIONS IN PERSONS WITH AND WITHOUT CYSTIC FIBROSIS. J Bacteriol. 1964 Feb;87:427–431. doi: 10.1128/jb.87.2.427-431.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- FINLAND M., JONES W. F., Jr, BARNES M. W. Occurrence of serious bacterial infections since introduction of antibacterial agents. J Am Med Assoc. 1959 Aug 29;170:2188–2197. doi: 10.1001/jama.1959.63010180008012. [DOI] [PubMed] [Google Scholar]
- Gingell J. C., Waterworth P. M. Dose of gentamicin in patients with normal renal function and renal impairment. Br Med J. 1968 Apr 6;2(5596):19–22. doi: 10.1136/bmj.2.5596.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HAYNES W. C. Pseudomonas aeruginosa--its characterization and identification. J Gen Microbiol. 1951 Nov;5(5 Suppl):939–950. doi: 10.1099/00221287-5-5-939. [DOI] [PubMed] [Google Scholar]
- LIU P. V., ABE Y., BATES J. L. The roles of various fractions of Pseudomonas aeruginosa in its pathogenesis. J Infect Dis. 1961 Mar-Apr;108:218–228. doi: 10.1093/infdis/108.2.218. [DOI] [PubMed] [Google Scholar]
- LIU P. V., MERCER C. B. GROWTH, TOXIGENICITY AND VIRULENCE OF PSEUDOMONAS AERUGINOSA. J Hyg (Lond) 1963 Dec;61:485–491. doi: 10.1017/s0022172400021100. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Maddocks J. L., May J. R. "Indirect pathogenicity" of penicillinase-producing enterobacteria in chronic bronchial infections. Lancet. 1969 Apr 19;1(7599):793–795. doi: 10.1016/s0140-6736(69)92063-7. [DOI] [PubMed] [Google Scholar]
- Shooter R. A., Walker K. A., Williams V. R., Horgan G. M., Parker M. T., Asheshov E. H., Bullimore J. F. Faecal carriage of Pseudomonas aeruginosa in hospital patients. Possible spread from patient to patient. Lancet. 1966 Dec 17;2(7477):1331–1334. doi: 10.1016/s0140-6736(66)92082-4. [DOI] [PubMed] [Google Scholar]
- WILLIAMS R., WILLIAMS E. D., HYAMS D. E. Cross-infection with Pseudomonas pyocyanea. Lancet. 1960 Feb 13;1(7120):376–379. doi: 10.1016/s0140-6736(60)90301-9. [DOI] [PubMed] [Google Scholar]