Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1973 Sep 15;3(5880):567–568. doi: 10.1136/bmj.3.5880.567

Treatment of Acute Myeloid Leukaemia according to the Hammersmith Protocol: Preliminary Report

W Paolino, L Resegotti, M Rossi, V Infelise
PMCID: PMC1586843  PMID: 4516626

Abstract

A preliminary report is given of a trial of the T.R.A.P. regimen (thioguanine, rubidomycin, cytosine arabinoside, and prednisolone) for the treatment of acute myeloid leukaemia. Out of 27 patients treated 13 (48·1%) obtained complete remission. The treatment was well tolerated and produced especially good results in elderly patients.

Full text

PDF
567

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Crowther D., Powles R. L., Bateman C. J., Beard M. E., Gauci C. L., Wrigley P. F., Malpas J. S., Fairley G. H., Scott R. B. Management of adult acute myelogenous leukaemia. Br Med J. 1973 Jan 20;1(5846):131–137. doi: 10.1136/bmj.1.5846.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Gee T. S., Yu K. P., Clarkson B. D. Treatment of adult acute leukemia with arabinosylcytosine and thioguanine. Cancer. 1969 May;23(5):1019–1032. doi: 10.1002/1097-0142(196905)23:5<1019::aid-cncr2820230506>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]
  3. Whitecar J. P., Jr, Bodey G. P., Freireich E. J., McCredie K. B., Hart J. S. Cyclophosphamide (NSC-26271), vincristine (NSC-67574), cytosine arabinoside (NSC-63878), and prednisone (NSC-10023) (COAP) combination chemotherapy for acute leukemia in adults. Cancer Chemother Rep. 1972 Aug;56(4):543–550. [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES