Abstract
Serum specimens from 162 patients with insulin-dependent diabetes of recent onset and 319 controls were tested for neutralizing antibodies to Coxsackie viruses types B1 to B5. Antibody to type B4 virus was more often found in diabetics than in controls, particularly in the 10-19 year age group. Though controls were not matched for geographical area it was thought that this was unlikely to explain the difference found. The month of onset of diabetes in the patients studied showed a pronounced seasonal incidence, which resembled that found in earlier studies.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Burch G. E., Tsui C. Y., Harb J. M., Colcolough H. L. Pathologic findings in the pancreas of mice infected with coxsackievirus B4. Arch Intern Med. 1971 Jul;128(1):40–47. [PubMed] [Google Scholar]
- Craighead J. E., McLane M. F. Diabetes mellitus: induction in mice by encephalomyocarditis virus. Science. 1968 Nov 22;162(3856):913–914. doi: 10.1126/science.162.3856.913. [DOI] [PubMed] [Google Scholar]
- Gamble D. R., Kinsley M. L., FitzGerald M. G., Bolton R., Taylor K. W. Viral antibodies in diabetes mellitus. Br Med J. 1969 Sep 13;3(5671):627–630. doi: 10.1136/bmj.3.5671.627. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gamble D. R., Taylor K. W. Seasonal incidence of diabetes mellitus. Br Med J. 1969 Sep 13;3(5671):631–633. doi: 10.1136/bmj.3.5671.631. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Harrison A. K., Bauer S. P., Murphy F. A. Viral pancreatitis: ultrastructural pathological effects of Coxsackievirus B3 infection in newborn mouse pancreas. Exp Mol Pathol. 1972 Oct;17(2):206–219. doi: 10.1016/0014-4800(72)90070-6. [DOI] [PubMed] [Google Scholar]
- Nerup J., Andersen O. O., Bendixen G., Egeberg J., Poulsen J. E. Anti-pancreatic cellular hypersensitivity in diabetes mellitus. Diabetes. 1971 Jun;20(6):424–427. doi: 10.2337/diab.20.6.424. [DOI] [PubMed] [Google Scholar]