Skip to main content
NCBI home page
British Medical Journal logoLink to British Medical Journal
. 1973 Dec 8;4(5892):586–589. doi: 10.1136/bmj.4.5892.586

From Phisohex to Hibiscrub

H G Smylie, J R C Logie, G Smith
PMCID: PMC1587723  PMID: 4586059

Abstract

In a field trial of three disinfectant-detergent preparations for the surgical scrub Hibiscrub (a 4% chlorhexidine detergent solution) maintained a significantly greater residual antibacterial action on the skin of the gloved hands of an operating team than was obtained with Disadine (povidone-iodine detergent preparation) (P<0·001). In comparison with Phisohex (3% hexachlorophane in detergent cream), the established surgical scrub of the operating team for many years, Hibiscrub maintained marginally more significant residual disinfection (P 0·05). Of the three preparations the members of the team found Hibiscrub to be more acceptable for use than either Disadine or Phisohex.

Full text

PDF
586

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baber K. G., Corner B., Duncan E. H., Eades S. M., Gillespie W. A., Walker S. C. A prospective study of staphylococcal infection and its prevention among infants and mothers after childbirth in hospital and at home. J Hyg (Lond) 1967 Sep;65(3):381–393. doi: 10.1017/s0022172400045903. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Curley A., Kimbrough R. D., Hawk R. E., Nathenson G., Finberg L. Dermal absorption of hexochlorophane in infants. Lancet. 1971 Aug 7;2(7719):296–297. doi: 10.1016/s0140-6736(71)91337-7. [DOI] [PubMed] [Google Scholar]
  3. Forfar J. O., Gould J. C., Maccabe A. F. Effect of hexachlorophane on incidence of staphylococcal and gram-negative infection in the newborn. Lancet. 1968 Jul 27;2(7561):177–179. doi: 10.1016/s0140-6736(68)92618-4. [DOI] [PubMed] [Google Scholar]
  4. Kimbrough R. D. Review of the toxicity of hexachlorophene. Arch Environ Health. 1971 Aug;23(2):119–122. doi: 10.1080/00039896.1971.10665967. [DOI] [PubMed] [Google Scholar]
  5. LOWBURY E. J., LILLY H. A., BULL J. P. Disinfection of the skin of operation sites. Br Med J. 1960 Oct 8;2(5205):1039–1044. doi: 10.1136/bmj.2.5205.1039. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. LOWBURY E. J., LILLY H. A. Disinfection of the hands of surgeons and nurses. Br Med J. 1960 May 14;1(5184):1445–1450. doi: 10.1136/bmj.1.5184.1445. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lilly H. A., Lowbury E. J. Disinfection of the skin: an assessment of some new preparations. Br Med J. 1971 Sep 18;3(5776):674–676. doi: 10.1136/bmj.3.5776.674. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lowbury E. J., Lilly H. A. Use of 4 per cent chlorhexidine detergent solution (Hibiscrub) and other methods of skin disinfection. Br Med J. 1973 Mar 3;1(5852):510–515. doi: 10.1136/bmj.1.5852.510. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Michaud R. N., McGrath M. B., Goss W. A. Improved experimental model for measuring skin degerming activity on the human hand. Antimicrob Agents Chemother. 1972 Jul;2(1):8–15. doi: 10.1128/aac.2.1.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. PLUECKHAHN V. D., BANKS J. ANTISEPSIS AND STAPHYLOCOCCAL DISEASE IN THE NEW-BORN CHILD. Med J Aust. 1963 Sep 28;2:519–523. [PubMed] [Google Scholar]
  11. SMYLIE H. G., WEBSTER C. U., BRUCE M. L. "Phisohex" and safer surgery. Br Med J. 1959 Oct 3;2(5152):606–609. doi: 10.1136/bmj.2.5152.606. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Selwyn S., Ellis H. Skin bacteria and skin disinfection reconsidered. Br Med J. 1972 Jan 15;1(5793):136–140. doi: 10.1136/bmj.1.5793.136. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES