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. 1973 Jan 20;1(5846):143–146. doi: 10.1136/bmj.1.5846.143

Effect of Orally Administered Prostaglandin E2 and its 15-Methyl Analogues on Gastric Secretion

S M M Karim, D C Carter, D Bhana, P Adaikan Ganesan
PMCID: PMC1588413  PMID: 4706806

Abstract

The effect of orally administered prostaglandin E2 and its synthetic 15-methyl analogues on gastric secretion in man was studied. The parent E2 compound did not inhibit basal secretion, whereas both the 15 (S) 15-methyl-E2 methyl ester and its isomer, 15 (R) 15-methyl-E2 methyl ester inhibited basal acid secretion. This action is likely to be a direct one on the parietal cell, and it could prove of value in the treatment of peptic ulcer.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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