Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1973 Mar 31;1(5856):761–765. doi: 10.1136/bmj.1.5856.761

Association between Atherosclerotic Diseases and Carboxyhaemoglobin Levels in Tobacco Smokers

Nicholas Wald, Susannah Howard, P G Smith, Knud Kjeldsen
PMCID: PMC1588915  PMID: 4694430

Abstract

In a cross-sectional study carboxyhaemoglobin (COHb) levels in tobacco smokers were found to provide a better indication of a person's risk of having developed certain atherosclerotic diseases, including ischaemic heart disease, than the smoking history. In the age group 30-69 years a person with a COHb level of 5% or more was found to be 21 times (lower 95% confidence limit 3·3 times) as likely to be affected by these diseases as another person of the same age and sex with similar smoking history and current smoking habits but with a COHb level of less than 3%.

Full text

PDF
761

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DOLL R., HILL A. B. MORTALITY IN RELATION TO SMOKING: TEN YEARS' OBSERVATIONS OF BRITISH DOCTORS. Br Med J. 1964 Jun 6;1(5396):1460–CONCL. doi: 10.1136/bmj.1.5396.1460. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Goldsmith J. R. Contribution of motor vehicle exhaust, industry, and cigarette smoking to community carbon monoxide exposures. Ann N Y Acad Sci. 1970 Oct 5;174(1):122–134. doi: 10.1111/j.1749-6632.1970.tb49779.x. [DOI] [PubMed] [Google Scholar]
  3. KANNEL W. B., DAWBER T. R., FRIEDMAN G. D., GLENNON W. E., MCNAMARA P. M. RISK FACTORS IN CORONARY HEART DISEASE. AN EVALUATION OF SEVERAL SERUM LIPIDS AS PREDICTORS OF CORONARY HEART DISEASE; THE FRAMINGHAM STUDY. Ann Intern Med. 1964 Nov;61:888–899. doi: 10.7326/0003-4819-61-5-888. [DOI] [PubMed] [Google Scholar]
  4. Kannel W. B., Castelli W. P., McNamara P. M. The coronary profile: 12-year follow-up in the Framingham study. J Occup Med. 1967 Dec;9(12):611–619. [PubMed] [Google Scholar]
  5. Kjeldsen K., Astrup P., Wanstrup J. Ultrastructural intimal changes in the rabbit aorta after a moderate carbon monoxide exposure. Atherosclerosis. 1972 Jul-Aug;16(1):67–82. doi: 10.1016/0021-9150(72)90009-3. [DOI] [PubMed] [Google Scholar]
  6. Lawther P. J., Commins B. T. Cigarette smoking and exposure to carbon monoxide. Ann N Y Acad Sci. 1970 Oct 5;174(1):135–147. doi: 10.1111/j.1749-6632.1970.tb49780.x. [DOI] [PubMed] [Google Scholar]
  7. Miettinen O. S. Estimation of relative risk from individually matched series. Biometrics. 1970 Mar;26(1):75–86. [PubMed] [Google Scholar]
  8. Webster W. S., Clarkson T. B., Lofland H. B. Carbon monoxide-aggravated atherosclerosis in the squirrel monkey. Exp Mol Pathol. 1970 Aug;13(1):36–50. doi: 10.1016/0014-4800(70)90083-3. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES