Skip to main content
NCBI home page
British Medical Journal logoLink to British Medical Journal
. 1973 Apr 28;2(5860):212–214. doi: 10.1136/bmj.2.5860.212

Bacteroides Infection among Hospital Patients

O A Okubadejo, P J Green, D J H Payne
PMCID: PMC1589375  PMID: 4700010

Abstract

In an 18-month period a total of 118 isolates of Bacteroides species, mainly Bacteroides fragilis, were grown from 112 hospital patients with various conditions. The infections were severe and were associated with serious operations such as intestinal surgery for carcinoma and postpartum hysterectomy. Blood cultures were often found to be positive too late in the course of infection for prompt and successful antibiotic therapy to be given. All the Bacteroides species tested were sensitive to clindamycin and co-trimoxazole. We suggest that clindamycin should be added to an empirical antibiotic regimen for the treatment of patients prone to the infection.

Full text

PDF
212

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bodner S. J., Koenig M. G., Goodman J. S. Bacteremic Bacteroides infections. Ann Intern Med. 1970 Oct;73(4):537–544. doi: 10.7326/0003-4819-73-4-537. [DOI] [PubMed] [Google Scholar]
  2. Ellner P. D., Wasilauskas B. L. Bacteroides septicemia in older patients. J Am Geriatr Soc. 1971 Apr;19(4):296–300. doi: 10.1111/j.1532-5415.1971.tb05369.x. [DOI] [PubMed] [Google Scholar]
  3. GESNER B. M., JENKIN C. R. Production of heparinase by Bacteroides. J Bacteriol. 1961 Apr;81:595–604. doi: 10.1128/jb.81.4.595-604.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GILLESPIE W. A., GUY J. Bacteroides in intra-abdominal sepsis: their sensitivity to antibiotics. Lancet. 1956 Jun 30;270(6931):1039–1041. doi: 10.1016/s0140-6736(56)90802-9. [DOI] [PubMed] [Google Scholar]
  5. GUNN A. A. Bacteroides septicaemia. J R Coll Surg Edinb. 1956 Sep;2(1):41–50. [PubMed] [Google Scholar]
  6. Gelb A. F., Seligman S. J. Bacteroidaceae bacteremia. Effect of age and focus of infection upon clinical course. JAMA. 1970 May 11;212(6):1038–1041. doi: 10.1001/jama.212.6.1038. [DOI] [PubMed] [Google Scholar]
  7. Ingham H. R., Selkon J. B., Codd A. A., Hale J. H. A study in vitro of the sensitivity to antibiotics of Bacteroides fragilis. J Clin Pathol. 1968 Jul;21(4):432–436. doi: 10.1136/jcp.21.4.432. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ingham H. R., Selkon J. B., Codd A. A., Hale J. H. The effect of carbon dioxide on the sensitivity of Bacteroides fragilis to certain antibiotics in vitro. J Clin Pathol. 1970 Apr;23(3):254–258. doi: 10.1136/jcp.23.3.254. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kislak J. W. The susceptibility of Bacteroides fragilis to 24 antibiotics. J Infect Dis. 1972 Mar;125(3):295–299. doi: 10.1093/infdis/125.3.295. [DOI] [PubMed] [Google Scholar]
  10. Moore W. E., Cato E. P., Holdeman L. V. Anaerobic bacteria of the gastrointestinal flora and their occurrence in clinical infections. J Infect Dis. 1969 Jun;119(6):641–649. doi: 10.1093/infdis/119.6.641. [DOI] [PubMed] [Google Scholar]
  11. Pearson H. E., Anderson G. V. Bacteroides infections and pregnancy. Obstet Gynecol. 1970 Jan;35(1):31–36. [PubMed] [Google Scholar]
  12. Tillotson J. R., Lerner A. M. Bacteroides pneumonias. Characteristics of cases with empyema. Ann Intern Med. 1968 Feb;68(2):308–317. doi: 10.7326/0003-4819-68-2-308. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES