Skip to main content
NCBI home page
British Medical Journal logoLink to British Medical Journal
. 1973 Jun 16;2(5867):638–641. doi: 10.1136/bmj.2.5867.638

Cardiovascular Effects of Acrylic Bone Cement in Rabbits and Cats

D Pelling, K R Butterworth
PMCID: PMC1589665  PMID: 4714847

Abstract

The cardiovascular responses to forcing acrylic bone cement, Plasticine, or soft paraffin wax into the medullary cavity of the femur have been studied in rabbits and cats. An acute fall in blood pressure, occurring within a few seconds of insertion, was demonstrated with each substance. In a few of the animals the blood pressure response had a second more protracted component and it is suggested that more than one mechanism is involved. The cardiovascular effects that have been observed in man when acrylic cement is used in prosthetic hip surgery also may be due to more than one mechanism.

Full text

PDF
638

Images in this article

639FIG. 1
on p.639
639FIG. 2
on p.639
640FIG. 3
on p.640
640FIG. 4
on p.640

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burgess D. M. Cardiac arrest and bone cement. Br Med J. 1970 Sep 5;3(5722):588–588. doi: 10.1136/bmj.3.5722.588-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cadle D., James M. L., Ling R. S., Piper R. F., Pryer D. L., Wilmshurst C. C. Cardiovascular responses after methylmethacrylic cement. Br Med J. 1972 Oct 14;4(5832):107–108. doi: 10.1136/bmj.4.5832.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Cohen C. A., Smith T. C. The intraoperative hazard of acrylic bone cement: report of a case. Anesthesiology. 1971 Nov;35(5):547–549. doi: 10.1097/00000542-197111000-00020. [DOI] [PubMed] [Google Scholar]
  4. Dandy D. J. Fat embolism following prosthetic replacement of the femoral head. Injury. 1971 Oct;3(2):85–88. doi: 10.1016/s0020-1383(71)80190-0. [DOI] [PubMed] [Google Scholar]
  5. Dustmann H. O., Schulitz K. P., Koch H. Fettembolie nach Anwendung von Knochenzement bei Hüftgelenksersatz. Tierexperimentelle Untersuchung. Arch Orthop Unfallchir. 1972;72(2):114–121. doi: 10.1007/BF00416526. [DOI] [PubMed] [Google Scholar]
  6. Ellis R. H., Mulvein J. Total replacement of the hip. Br Med J. 1972 May 27;2(5812):528–528. doi: 10.1136/bmj.2.5812.528-c. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Frost P. M. Cardiac arrest and bone cement. Br Med J. 1970 Aug 29;3(5721):524–524. doi: 10.1136/bmj.3.5721.524. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Gresham G. A., Kuczynski A., Rosborough D. Fatal fat embolism following replacement arthroplasty for transcervical fractures of femur. Br Med J. 1971 Jun 12;2(5762):617–619. doi: 10.1136/bmj.2.5762.617. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Homsy C. A., Tullos H. S., Anderson M. S., Diferrante N. M., King J. W. Some physiological aspects of prosthesis stabilization with acrylic polymer. Clin Orthop Relat Res. 1972 Mar-Apr;83:317–328. doi: 10.1097/00003086-197203000-00052. [DOI] [PubMed] [Google Scholar]
  10. Hyland J., Robins R. H. Cardiac arrest and bone cement. Br Med J. 1970 Oct 17;4(5728):176–177. doi: 10.1136/bmj.4.5728.176-c. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ling R. S., James M. L. Blood pressure and bone cement. Br Med J. 1971 May 15;2(5758):404–404. doi: 10.1136/bmj.2.5758.404-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Newens A. F., Volz R. G. Severe hypotension during prosthetic hip surgery with acrylic bone cement. Anesthesiology. 1972 Mar;36(3):298–300. doi: 10.1097/00000542-197203000-00021. [DOI] [PubMed] [Google Scholar]
  13. Peebles D. J., Ellis R. H., Stride S. D., Simpson B. R. Cardiovascular effects of methylmethacrylate cement. Br Med J. 1972 Feb 5;1(5796):349–351. doi: 10.1136/bmj.1.5796.349. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Phillips H., Cole P. V., Lettin A. W. Cardiovascular effects of implanted acrylic bone cement. Br Med J. 1971 Aug;3(5772):460–461. doi: 10.1136/bmj.3.5772.460. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Powell J. N., McGrath P. J., Lahiri S. K., Hill P. Cardiac arrest associated with bone cement. Br Med J. 1970 Aug 8;3(5718):326–326. doi: 10.1136/bmj.3.5718.326. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Sevitt S. Fat embolism in patients with fractured hips. Br Med J. 1972 Apr 29;2(5808):257–262. doi: 10.1136/bmj.2.5808.257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Stokes J. Infection in the nursery. Br Med J. 1970 Aug 29;3(5721):523–523. doi: 10.1136/bmj.3.5721.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Thomas T. A., Sutherland I. C., Waterhouse T. D. Cold curing acrylic bone cement. A clinical study of the cardiovascular side effects during hip joint replacement. Anaesthesia. 1971 Jul;26(3):298–303. doi: 10.1111/j.1365-2044.1971.tb04788.x. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES