Abstract
Three cases of athetoid cerebral palsy after hypoxic-ischaemic encephalopathy (HIE) are reported. All three neonates had haemorrhagic lesions in the basal ganglia and thalami on magnetic resonance imaging (MRI). Prior cranial ultrasound had detected the lesions in only two cases. In all three children athetoid movements began within the first year of life. Follow up MRI scans showed bilateral symmetrical cystic lesions in the posterior putamen. Although haemorrhagic lesions within the basal ganglia are a common MRI finding in neonates with HIE, few of these babies develop athetoid cerebral palsy. We believe this to be the first report of discrete cystic lesions found in the basal ganglia of children with athetoid cerebral palsy.
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- Brun A., Kyllerman M. Clinical, pathogenetic and neuropathological correlates in dystonic cerebral palsy. Eur J Pediatr. 1979 May 18;131(2):93–104. doi: 10.1007/BF00447471. [DOI] [PubMed] [Google Scholar]
- Connolly A. M., Volpe J. J. Clinical features of bilirubin encephalopathy. Clin Perinatol. 1990 Jun;17(2):371–379. [PubMed] [Google Scholar]
- Donn S. M., Bowerman R. A., DiPietro M. A., Gebarski S. S. Sonographic appearance of neonatal thalamic-striatal hemorrhage. J Ultrasound Med. 1984 May;3(5):231–233. doi: 10.7863/jum.1984.3.5.231. [DOI] [PubMed] [Google Scholar]
- Hagberg G., Hagberg G., Olow I. The changing panorama of cerebral palsy in Sweden 1954-1970. II. Analysis of the various syndromes. Acta Paediatr Scand. 1975 Mar;64(2):193–200. doi: 10.1111/j.1651-2227.1975.tb03821.x. [DOI] [PubMed] [Google Scholar]
- Johnson M. A., Pennock J. M., Bydder G. M., Steiner R. E., Thomas D. J., Hayward R., Bryant D. R., Payne J. A., Levene M. I., Whitelaw A. Clinical NMR imaging of the brain in children: normal and neurologic disease. AJR Am J Roentgenol. 1983 Nov;141(5):1005–1018. doi: 10.2214/ajr.141.5.1005. [DOI] [PubMed] [Google Scholar]
- Johnston M. V., Singer H. S. Brain neurotransmitters and neuromodulators in pediatrics. Pediatrics. 1982 Jul;70(1):57–68. [PubMed] [Google Scholar]
- Kotagal S., Toce S. S., Kotagal P., Archer C. R. Symmetric bithalamic and striatal hemorrhage following perinatal hypoxia in a term infant. J Comput Assist Tomogr. 1983 Apr;7(2):353–355. doi: 10.1097/00004728-198304000-00033. [DOI] [PubMed] [Google Scholar]
- Kreusser K. L., Schmidt R. E., Shackelford G. D., Volpe J. J. Value of ultrasound for identification of acute hemorrhagic necrosis of thalamus and basal ganglia in an asphyxiated term infant. Ann Neurol. 1984 Sep;16(3):361–363. doi: 10.1002/ana.410160315. [DOI] [PubMed] [Google Scholar]
- MALAMUD N. Status marmoratus; a form of cerebral palsy following either birth injury or inflammation of the central nervous system. J Pediatr. 1950 Oct;37(4):610–619. doi: 10.1016/s0022-3476(50)80272-x. [DOI] [PubMed] [Google Scholar]
- Myers R. E. Four patterns of perinatal brain damage and their conditions of occurrence in primates. Adv Neurol. 1975;10:223–234. [PubMed] [Google Scholar]
- PAINE R. S. THE EVOLUTION OF INFANTILE POSTURAL REFLEXES IN THE PRESENCE OF CHRONIC BRAIN SYNDROMES. Dev Med Child Neurol. 1964 Aug;6:345–361. doi: 10.1111/j.1469-8749.1964.tb08136.x. [DOI] [PubMed] [Google Scholar]
- POLANI P. E. The natural clinical history of choreo-athetoid cerebral palsy. Guys Hosp Rep. 1959;108(1):32–45. [PubMed] [Google Scholar]
- Voit T., Lemburg P., Neuen E., Lumenta C., Stork W. Damage of thalamus and basal ganglia in asphyxiated full-term neonates. Neuropediatrics. 1987 Aug;18(3):176–181. doi: 10.1055/s-2008-1052475. [DOI] [PubMed] [Google Scholar]