Abstract
Between 1971 and 1975 the mean annual incidence of human Salmonella dublin infection in California increased more than five-fold. Investigation of the increase showed an association with exposure to raw milk in 44 out of 113 cases. Of these 44 patients, 35 had used certified raw milk from a single dairy. Faecal swabs confirmed S dublin infection in the dairy herd and the milk, and so a pasteurisation order was issued. S dublin appears to be an unusually invasive and life-threatening salmonella serotype: 65% of isolations were obtained from non-faecal specimens (mainly blood cultures), 89 patients (80%) were admitted to hospital and 22 patients died. Almost three-quarters of the patients were aged 20 or over, and half had serious underlying diseases, particularly leukaemias and lymphomas. Five patients presented with infected vascular lesions that included aneurysms with abscesses and infections of previous arterial graft sites. The public's increasing desire for a "health food" such as raw milk should be tempered with an appreciation of its attendant risk to health.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Aserkoff B., Schroeder S. A., Brachman P. S. Salmonellosis in the United States--a five-year review. Am J Epidemiol. 1970 Jul;92(1):13–24. doi: 10.1093/oxfordjournals.aje.a121175. [DOI] [PubMed] [Google Scholar]
- BLACK P. H., KUNZ L. J., SWARTZ M. N. Salmonellosis--a review of some unusual aspects. N Engl J Med. 1960 Apr 21;262:811–contd. doi: 10.1056/NEJM196004212621606. [DOI] [PubMed] [Google Scholar]
- Bauer H. Growing problem of salmonellosis in modern society. Medicine (Baltimore) 1973 Jul;52(4):323–330. doi: 10.1097/00005792-197307000-00011. [DOI] [PubMed] [Google Scholar]
- Chmel H., Armstrong D. Salmonella oslo. A focal outbreak in a hospital. Am J Med. 1976 Feb;60(2):203–208. doi: 10.1016/0002-9343(76)90429-0. [DOI] [PubMed] [Google Scholar]
- Collins R. N., Treger M. D., Goldsby J. B., Boring J. R., 3rd, Coohon D. B., Barr R. N. Interstate outbreak of Salmonella newbrunswick infection traced to powdered milk. JAMA. 1968 Mar 4;203(10):838–844. [PubMed] [Google Scholar]
- Craven P. C., Mackel D. C., Baine W. B., Barker W. H., Gangarosa E. J. International outbreak of Salmonella Eastbourne infection traced to contaminated chocolate. Lancet. 1975 Apr 5;1(7910):788–792. doi: 10.1016/s0140-6736(75)92446-0. [DOI] [PubMed] [Google Scholar]
- HOOK E. W. Salmonellosis: certain factors influencing the interaction of Salmonella and the human host. Bull N Y Acad Med. 1961 Jul;37:499–512. [PMC free article] [PubMed] [Google Scholar]
- Lang D. J., Kunz L. J., Martin A. R., Schroeder S. A., Thomson L. A. Carmine as a source of nosocomial salmonellosis. N Engl J Med. 1967 Apr 13;276(15):829–832. doi: 10.1056/NEJM196704132761502. [DOI] [PubMed] [Google Scholar]
- Marth E. H. Salmonellae and salmonellosis associated with milk and milk products. A review. J Dairy Sci. 1969 Mar;52(3):283–315. doi: 10.3168/jds.S0022-0302(69)86552-5. [DOI] [PubMed] [Google Scholar]
- Pearson H. E., Grant W. J. Presumed transmission of salmonella by sigmoidoscope. Calif Med. 1970 Feb;112(2):23–25. [PMC free article] [PubMed] [Google Scholar]
- Wilder A. N., MacCready R. A. Isolation of salmonella from poultry, poultry products and poultry processing plants in Massachusetts. N Engl J Med. 1966 Jun 30;274(26):1453–1460. doi: 10.1056/NEJM196606302742601. [DOI] [PubMed] [Google Scholar]
- ZAK F. G., STRAUSS L., SAPHRA I. Rupture of diseased large arteries in the course of enterobacterial (Salmonella) infections. N Engl J Med. 1958 Apr 24;258(17):824–828. doi: 10.1056/NEJM195804242581702. [DOI] [PubMed] [Google Scholar]