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. 1979 Jun 16;1(6178):1599–1601. doi: 10.1136/bmj.1.6178.1599

General anaesthesia in sickle-cell disease.

J Homi, J Reynolds, A Skinner, W Hanna, G Serjeant
PMCID: PMC1599173  PMID: 466140

Abstract

General anaesthesia was administered on 284 occasions to 200 patients with sickle-cell disease at one hospital during July 1958 to June 1978. No intraoperative but six postoperative deaths occurred. The management of anaesthesia may have contributed to two of the postoperative deaths. Clinically uneventful anaesthesia did not appear to provoke severe sickling crises or to be responsible for mortality, but a contribution to postoperative morbidity could not be excluded. A simple, careful anaesthetic technique and selective but not routine blood transfusion appears to be associated with minimal anaesthetic morbidity and mortality in patients with sickle-cell disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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