Abstract
In a prospective study 29 patients with urinary tract infections caused by sulphonamide-sensitive organisms were treated with a single oral dose of the short-acting sulphonamide sulphafurazole. Twenty-seven (93%) of the 29 patients--and possibly all 29--were cured of their infections. There was no difference in the recurrence rates after single-dose treatment and treatment for 10 days or more. Six out of eight strains of Escherichia coli causing early recurrences were sensitive to sulphonamides. These results suggest that uncomplicated infections may safely and successfully be treated by a single oral dose of a short-acting sulphonamide.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bailey R. R., Abbott G. D. Treatment of urinary-tract infection with a single dose of amoxycillin. Nephron. 1977;18(6):316–320. doi: 10.1159/000180849. [DOI] [PubMed] [Google Scholar]
- Bergström T., Lincoln K., Orskov F., Orskov I., Winberg J. Studies of urinary tract infections in infancy and childhood. 8. Reinfection vs. relapse in recurrent urinary tract infections. Evaluation by means of identification of infecting organisms. J Pediatr. 1967 Jul;71(1):13–20. doi: 10.1016/s0022-3476(67)80224-5. [DOI] [PubMed] [Google Scholar]
- Bergström T., Lincoln K., Redin B., Winberg J. Studies of urinary tract infections in infancy and childhood. X. Short or long-term treatment in girls with first or second-time urinary tract infections uncomplicated by obstructive urological abnormalities. Acta Paediatr Scand. 1968 May;57(3):186–194. doi: 10.1111/j.1651-2227.1968.tb04677.x. [DOI] [PubMed] [Google Scholar]
- Ericsson H. M., Sherris J. C. Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217(Suppl):1+–1+. [PubMed] [Google Scholar]
- Fang L. S., Tolkoff-Rubin N. E., Rubin R. H. Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic. N Engl J Med. 1978 Feb 23;298(8):413–416. doi: 10.1056/NEJM197802232980802. [DOI] [PubMed] [Google Scholar]
- Grüneberg R. N., Brumfitt W. Single-dose treatment of acute urinary tract infection: a controlled trial. Br Med J. 1967 Sep 9;3(5566):649–651. doi: 10.1136/bmj.3.5566.649. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kaijser B., Hanson L. A., Jodal U., Lidin-Janson G., Robbins J. B. Frequency of E. coli K antigens in urinary-tract infections in children. Lancet. 1977 Mar 26;1(8013):663–666. doi: 10.1016/s0140-6736(77)92111-0. [DOI] [PubMed] [Google Scholar]
- Källenius G., Winberg J. Bacterial adherence to periurethral epithelial cells in girls prone to urinary-tract infections. Lancet. 1978 Sep 9;2(8089):540–543. doi: 10.1016/s0140-6736(78)92880-5. [DOI] [PubMed] [Google Scholar]
- Lidin-Janson G., Falsen E., Jodal U., Kaijser B., Lincoln K. Characteristics of antibiotic-resistant Escherichia coli in the rectum of healthy school-children. J Med Microbiol. 1977 Aug;10(3):299–308. doi: 10.1099/00222615-10-3-299. [DOI] [PubMed] [Google Scholar]
- Lincoln K., Lidin-Janson G., Winberg J. Resistant urinary infections resulting from changes in resistance pattern of faecal flora induced by sulphonamide and hospital environment. Br Med J. 1970 Aug 8;3(5718):305–309. doi: 10.1136/bmj.3.5718.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PRYLES C. V., GLAGOVSKY A. SEROLOGICAL CHARACTERIZATION OF ESCHERICHIA COLI. STUDY IN ACUTE AND RECURRENT URINARY TRACT INFECTIONS IN INFANTS AND CHILDREN. Pediatrics. 1965 Aug;36:219–224. [PubMed] [Google Scholar]
- Ronald A. R., Boutros P., Mourtada H. Bacteriuria localization and response to single-dose therapy in women. JAMA. 1976 Apr 26;235(17):1854–1856. [PubMed] [Google Scholar]
- Smellie J. M., Katz G., Grüneberg R. N. Controlled trial of prophylactic treatment in childhood urinary-tract infection. Lancet. 1978 Jul 22;2(8082):175–178. doi: 10.1016/s0140-6736(78)91919-0. [DOI] [PubMed] [Google Scholar]