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. 1978 Jan 21;1(6106):140–142. doi: 10.1136/bmj.1.6106.140

Comparison of serum oestrogen concentrations in post-menopausal women taking oestrone sulphate and oestradiol.

A B Anderson, E Sklovsky, L Sayers, P A Steele, A C Turnbull
PMCID: PMC1602815  PMID: 620226

Abstract

Mean serum concentrations of oestradiol-17beta, oestrone, and oestrone sulphate in postmenopausal women were the same when measured up to six hours after treatment with either piperazine oestrone sulphate 1.5 mg or oestradiol valerate 2 mg. Maximum concentrations of oestradiol were less than those of oestrone, but oestrone sulphate reached concentrations about 30 times higher than those of oestrone. The rapid conversion of oestradiol valerate to oestrone and oestrone sulphate does not support the suggestion that in menopausal women oestradiol is less likely to be associated with a risk of endometrial carcinoma than oestrone sulphate, since the two preparations appear to become identical after ingestion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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