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. 1977 Jan 29;1(6056):259–261. doi: 10.1136/bmj.1.6056.259

Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels.

P Wilson, R T Ramsden
PMCID: PMC1604140  PMID: 837060

Abstract

Electrocochleography was performed on three patients to monitor the intravenous administration of tobramycin. When peak serum tobramycin levels exceeded 8-10 mug/ml an immediate dramatic reduction in cochlear output was observed, which recovered fully as serum levels fell. The patients had no auditory or vestibular symptoms either during or after treatment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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