Skip to main content
PMC home page
British Medical Journal logoLink to British Medical Journal
. 1978 May 13;1(6122):1235–1237. doi: 10.1136/bmj.1.6122.1235

Factors influencing the incidence of neonatal jaundice.

L Friedman, P J Lewis, P Clifton, C J Bulpitt
PMCID: PMC1604617  PMID: 647211

Abstract

A retrospective study of 12 461 single births confirmed an association between maternal oxytocin infusion and neonatal jaundice. The effect of oxytocin on jaundice was independent of gestational age at birth, sex, race, epidural anaesthesia, method of delivery, and birth weight, each of which was significantly associated with neonatal jaundice. The effect of oxytocin was, however, small, producing a calculated mean increase in peak plasma bilirubin concentration of 8.6 mumol/1 (0.5 mg/100 ml); this excess was independent of sex and less than the effect of the baby being born one week earlier.

Full text

PDF
1235

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beazley J. M., Alderman B. Neonatal hyperbilirubinaemia following the use of oxytocin in labour. Br J Obstet Gynaecol. 1975 Apr;82(4):265–271. doi: 10.1111/j.1471-0528.1975.tb00632.x. [DOI] [PubMed] [Google Scholar]
  2. Boggs T. R., Jr, Hardy J. B., Frazier T. M. Correlation of neonatal serum total bilirubin concentrations and developmental status at age eight months. A preliminary report from the collaborative project. J Pediatr. 1967 Oct;71(4):553–560. doi: 10.1016/s0022-3476(67)80107-0. [DOI] [PubMed] [Google Scholar]
  3. Boylan P. Oxytocin and neonatal jaundice. Br Med J. 1976 Sep 4;2(6035):564–565. doi: 10.1136/bmj.2.6035.564-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Campbell N., Harvey D., Norman A. P. Increased frequency of neonatal jaundice in a maternity hospital. Br Med J. 1975 Jun 7;2(5970):548–552. doi: 10.1136/bmj.2.5970.548. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Chew W. C., Swann I. L. Influence of simultaneous low amniotomy and oxytocin infusion and other maternal factors on neonatal jaundice: a prospective study. Br Med J. 1977 Jan 8;1(6053):72–73. doi: 10.1136/bmj.1.6053.72. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Davies D. P., Gomersall R., Robertson R., Gray O. P., Turnbull A. C. Neonatal jaundice and maternal oxytocin infusion. Br Med J. 1973 Sep 1;3(5878):476–477. doi: 10.1136/bmj.3.5878.476. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Fenwick J. D. Neonatal jaundice as a cause of deafness. J Laryngol Otol. 1975 Sep;89(9):925–932. doi: 10.1017/s0022215100081202. [DOI] [PubMed] [Google Scholar]
  8. Friedman E. A., Sachtleben M. R. Neonatal jaundice in association with oxytocin stimulation of labour and operative delivery. Br Med J. 1976 Jan 24;1(6003):198–199. doi: 10.1136/bmj.1.6003.198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gate J. M. Syntometrine as a possible cause of neonatal jaundice. Br Med J. 1978 Jan 7;1(6104):49–49. doi: 10.1136/bmj.1.6104.49-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gluck L., Kulovich M. V. Lecithin-sphingomyelin ratios in amniotic fluid in normal and abnormal pregnancy. Am J Obstet Gynecol. 1973 Feb 15;115(4):539–546. doi: 10.1016/0002-9378(73)90404-3. [DOI] [PubMed] [Google Scholar]
  11. Singhi S., Singh M. Oxytocin induction and neonatal hyperbilirubinaemia. Br Med J. 1977 Oct 15;2(6093):1028–1028. doi: 10.1136/bmj.2.6093.1028-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Trolle D. Decrease of total serum-bilirubin concentration in newborn infants after phenobarbitone treatment. Lancet. 1968 Sep 28;2(7570):705–708. doi: 10.1016/s0140-6736(68)90750-2. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES