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British Medical Journal logoLink to British Medical Journal
. 1977 Mar 19;1(6063):739–741. doi: 10.1136/bmj.1.6063.739

Proliferative diabetic retinopathy: treatment with xenon-arc photocoagulation. Interim report of multicentre randomised controlled trial.

PMCID: PMC1605609  PMID: 322791

Abstract

One hundred patients with symmetrical proliferative diabetic retinopathy had one eye randomly chosen for treatment with xenonarc photocoagulation while the other was left untreated as a control. Patients were subdivided into those with new vessels on both optic discs and those with only peripheral new vessels. In patients with new vessels on the optic discs the vision of the untreated eyes deteriorated more than that of the treated eyes and the difference in deterioration was significant after one, two, and three years. There was no such difference in patients who had only peripheral new vessels. Eighteen patients had become blind in one or both eyes by the last assessment, but only one patient became blind in the treated eye without concomitant blindness in the untreated eye. Thirteen were blind only in the untreated eye. Both photographic and ophthalmoscopic examinations showed that new vessels on the disc regressed more in the treated eyes than in the untreated ones. As some forms of diabetic retinopathy are now treatable, early diagnosis and evaluation is increasingly important.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASHTON N. Arteriolar involvement in diabetic retinopathy. Br J Ophthalmol. 1953 May;37(5):282–292. doi: 10.1136/bjo.37.5.282. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BEETHAM W. P. VISUAL PROGNOSIS OF PROLIFERATING DIABETIC RETINOPATHY. Br J Ophthalmol. 1963 Oct;47:611–619. doi: 10.1136/bjo.47.10.611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Caird F. I., Burditt A. F., Draper G. J. Diabetic retinopathy. A further study of prognosis for vision. Diabetes. 1968 Mar;17(3):121–123. doi: 10.2337/diab.17.3.121. [DOI] [PubMed] [Google Scholar]
  4. Deckert T., Simonsen S. E., Poulsen J. E. Prognosis of proliferative retinopathy in juvenile diabetics. Diabetes. 1967 Oct;16(10):728–733. doi: 10.2337/diab.16.10.728. [DOI] [PubMed] [Google Scholar]
  5. Kohner E. M., Panisset A., Cheng H., Fraser T. R. Diabetic retinopathy: new vessels arising from the optic disc. I. Grading system and natural history. Diabetes. 1971 Dec;20(12):816–823. doi: 10.2337/diab.20.12.816. [DOI] [PubMed] [Google Scholar]
  6. Oakley N., Hill D. W., Joplin G. F., Kohner E. M., Fraser T. R. Diabetic retinopathy. I. The assessment of severity and progress by comparison with a set of standard fundus photographs. Diabetologia. 1967 Aug;3(4):402–405. doi: 10.1007/BF02342633. [DOI] [PubMed] [Google Scholar]
  7. WISE G. N. Retinal neovascularization. Trans Am Ophthalmol Soc. 1956;54:729–826. [PMC free article] [PubMed] [Google Scholar]

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